Results 91 to 100 of about 11,135,694 (289)

Using the adjuvants during infusion of local anaestetics into caudal-epidural space in newborns

open access: yesPatologìâ, 2012
Markers of stress and central haemodynamics were investigated in 45 newborns. General anesthesia and caudal infusion of local anesthetics were combined in 15 newborns. Promedol and clonidine were added to local anesthetics in 15 newborns.
M. Yu. Kurochkin
doaj   +1 more source

Anesthetics and cerebral metabolism.

open access: yes, 2004
PURPOSE OF REVIEW: This review focuses on the utilization of the effects of general anesthetics on cerebral metabolism as revealed by imaging for therapeutic and preventive purposes, for understanding mechanisms of anesthetic action, and for elucidating ...
Gyulai, Ferenc E
core  

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

open access: yesArthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet   +11 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato   +27 more
wiley   +1 more source

Modulatory mechanism of the paraventricular thalamus (PVT) under general anesthesia

open access: yesFrontiers in Pharmacology
The paraventricular thalamus (PVT) is a critical brain region involved in controlling sleep-wakefulness. Many neural nuclei and circuits regulate consciousness under both sleep-wakefulness and general anesthesia, suggesting that a common neural mechanism
Jia Li, Yiyong Wei, Donghang Zhang
doaj   +1 more source

ANESTHETIC, ANALGETIC, HYPNOTIC – ARE THE TERMS IMPORTANT?

open access: yesВестник анестезиологии и реаниматологии, 2017
The review is devoted to pharmacology of the general anesthesia in the light of current understanding of this event and as a medical technique. The discussion covers the classification of medications used for general anesthesia basing on action mechanisms
A. E. Karelov   +2 more
doaj   +1 more source

General Anesthetics and Neurotoxicity [PDF]

open access: yesAnesthesiology Clinics, 2016
Over a decade ago, alarming findings were reported that exposure of the very young and very old animals to clinically used general anesthetics could be detrimental to their brains. The evidence presented suggested that the exposure to commonly used gaseous and intravenous general anesthetics induces the biochemical and morphologic changes in the ...
openaire   +2 more sources

General anesthetics in brain injury: friends or foes?

open access: yes, 2014
General anesthesia-induced pharmacological protection of the central nervous system following injury has been under intense investigations during the past four decades.
Vutskits, Laszlo
core  

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

The dual effects of anesthetics on glial cells: a review of neuroprotection and neurotoxicity

open access: yesFrontiers in Pharmacology
Glial cells—comprising astrocytes, microglia, and oligodendrocytes—are fundamental to central nervous system (CNS) homeostasis, yet their interactions with anesthetics are not fully elucidated.
Xiaodong Wang   +4 more
doaj   +1 more source

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