Results 11 to 20 of about 45,779 (252)
, 2021 General anesthetics are administered to approximately 50 million patients each year in the United States. Anesthetic vapors and gases are also widely used in dentists’ offices, veterinary clinics, and laboratories for animal research. All the volatile anesthetics that are currently used are halogenated compounds destructive to the ozone layer.
Shanthi Paulraj, Mageshwaran Lakshmanan
+5 more sources
Molecular mechanisms of general anesthesia [PDF]
Korean Journal of Anesthesiology, 2010 General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission.
Yong Son
doaj +1 more source
General Anesthetics Commonly Used for Laboratory Animals
Shiyan dongwu yu bijiao yixue, 2022 General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
doaj +1 more source
Structural interplay of anesthetics and paralytics on muscle nicotinic receptors
Nature Communications, 2023 General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami +3 more
doaj +1 more source
The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee +6 more
doaj +1 more source
The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Korean Journal of Anesthesiology, 2022 Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
doaj +1 more source
BMC Anesthesiology, 2021 Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao +3 more
doaj +1 more source
Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling
Frontiers in Oncology, 2021 Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Jiaqiang Wang +5 more
doaj +1 more source
Cell Reports, 2018 Summary: Ion channel modulation by general anesthetics is a vital pharmacological process with implications for receptor biophysics and drug development. Functional studies have implicated conserved sites of both potentiation and inhibition in pentameric
Zaineb Fourati +7 more
doaj +1 more source
A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
Brain Sciences, 2014 The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj +1 more source