Structural interplay of anesthetics and paralytics on muscle nicotinic receptors [PDF]
Nature Communications, 2023 General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of ...
Umang Goswami +3 more
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Effect of general anesthetics on the developing brain
Journal of Anaesthesiology Clinical Pharmacology, 2012 Studies on rodents and subhuman primates suggest that prolonged exposure to general anesthetics may induce widespread neuronal cell death and neurological sequelae; seriously questioning the safety of pediatric anesthesia.
S Velayudha Reddy
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Effect of Local and General Anesthetics on Interfacial Water. [PDF]
PLoS ONE, 2016 Water undergoes structural change as it interfaces with hydrophilic surfaces, including the many hydrophilic surfaces within the cell. This interfacial water has become known as "Exclusion Zone (EZ) water" or "fourth-phase water" [1].We tested the ...
Nenad Kundacina +2 more
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Intravenous anesthetics have differential effects on human potassium channels
Acta Biochimica et Biophysica SinicaGeneral anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying +9 more
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Research progress on mitochondrial mechanisms of sensitivity to inhalational anesthetics [PDF]
Zhongguo linchuang yanjiuExperimental animals and people have different sensitivity to inhalational anesthetics, which is related to the depth of anesthesia during general anesthesia and the perioperative safety of patients.
CHENG Sijing*, WEI Yiyong, WANG Haiying
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Effects of general anesthetics on visceral pain transmission in the spinal cord [PDF]
Molecular Pain, 2008 Current evidence suggests an analgesic role for the spinal cord action of general anesthetics; however, the cellular population and intracellular mechanisms underlying anti-visceral pain by general anesthetics still remain unclear.
Yue Yun +5 more
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General Anesthetics Commonly Used for Laboratory Animals
Shiyan dongwu yu bijiao yixue, 2022 General anesthetics used for laboratory animals are mostly controlled drugs, and are subject to strict supervision by the competent government agency in China.
LU Xiao +5 more
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, 2021 General anesthetics are administered to approximately 50 million patients each year in the United States. Anesthetic vapors and gases are also widely used in dentists’ offices, veterinary clinics, and laboratories for animal research. All the volatile anesthetics that are currently used are halogenated compounds destructive to the ozone layer.
Shanthi Paulraj, Mageshwaran Lakshmanan
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The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis [PDF]
Korean Journal of Anesthesiology, 2022 Background Diabetes is a risk factor for postoperative complications. Previous meta-analyses have shown that elevated glycated hemoglobin (HbA1c) levels are associated with postoperative complications in various surgical populations. However, this is the
Joanna K. L. Wong +5 more
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The changes of pharmacokinetic behavior of the medical substances as a consequence of the „in vivo” interaction with general anesthetics [PDF]
Medicamentul Veterinar, 2007 General anesthetics are substances which produce a reversible state of unconsciousness and insensibility. Inaddition to these principal effects, anesthetics modify almost always, the other functions of the organism.
Năstasă V.,, Maria-Magdalena Nechifor
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