Results 21 to 30 of about 77,660 (291)
A Common Neuroendocrine Substrate for Diverse General Anesthetics and Sleep. [PDF]
Neuron, 2019 Jiang-Xie LF +6 more
europepmc +2 more sources
Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]
, 2015 BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR +8 more
core +1 more source
Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]
, 2018 Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W. +4 more
core +2 more sources
Cell Reports, 2018 Summary: Ion channel modulation by general anesthetics is a vital pharmacological process with implications for receptor biophysics and drug development. Functional studies have implicated conserved sites of both potentiation and inhibition in pentameric
Zaineb Fourati +7 more
doaj +1 more source
A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
Brain Sciences, 2014 The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj +1 more source
General Anesthetics and Neurotoxicity: How Much Do We Know? [PDF]
Anesthesiol Clin, 2016 Jevtovic-Todorovic V.
europepmc +3 more sources
BMC Anesthesiology, 2018 Background This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy ...
Hong Yu, Lu Zhang, Ye Ma, Hai Yu
doaj +1 more source
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
, 2009 Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
core +2 more sources
Frontiers in Synaptic Neuroscience, 2022 General anesthetics disrupt brain processes involved in consciousness by altering synaptic patterns of excitation and inhibition. In the cerebral cortex and hippocampus, GABAergic inhibition is largely mediated by inhibitory interneurons, a heterogeneous
Iris A. Speigel +2 more
doaj +1 more source
Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources