Results 21 to 30 of about 77,182 (352)

Volatile Anesthetics Regulate Anti-Cancer Relevant Signaling

open access: yesFrontiers in Oncology, 2021
Volatile anesthetics are widely used inhalation anesthetics in clinical anesthesia. In recent years, the regulation of anti-cancer relevant signaling of volatile anesthetics has drawn the attention of investigators.
Jiaqiang Wang   +5 more
doaj   +1 more source

New patents on topical anesthetics. [PDF]

open access: yes, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano   +6 more
core   +1 more source

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

open access: yes, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR   +8 more
core   +1 more source

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels

open access: yesCell Reports, 2018
Summary: Ion channel modulation by general anesthetics is a vital pharmacological process with implications for receptor biophysics and drug development. Functional studies have implicated conserved sites of both potentiation and inhibition in pentameric
Zaineb Fourati   +7 more
doaj   +1 more source

A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain

open access: yesBrain Sciences, 2014
The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj   +1 more source

Research progress on molecular mechanisms of general anesthetic-induced neurotoxicity and cognitive impairment in the developing brain

open access: yesFrontiers in Neurology, 2022
General anesthetics-induced neurotoxicity and cognitive impairment in developing brains have become one of the current research hotspots in the medical science community.
Jiaojiao Wang, Jiaojiao Wang, Zhihui Liu
doaj   +1 more source

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

open access: yes, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L   +5 more
core   +1 more source

Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]

open access: yes, 2018
Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W.   +4 more
core   +2 more sources

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]

open access: yes, 2009
Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G.   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy