Results 51 to 60 of about 7,142,009 (388)

The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brain [PDF]

Korean Journal of Anesthesiology, 2014
BackgroundGeneral anesthetics induce neuronal apoptosis in the immature brain. Regional anesthesia using local anesthetics can be an alternative to general anesthesia.
Ji-Hyun Lee, Yong-Hee Park, Hyun-Gul Song, Hee-Pyoung Park, Hee-Soo Kim, Chong-Sung Kim, Jin-Tae Kim   +6 more
doaj   +1 more source

Volatile anesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration

BMC Anesthesiology, 2021
Background Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics on spontaneous respiration in non-
Xuechao Hao, Mengchan Ou, Yu Li, Cheng Zhou   +3 more
doaj   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

General anesthetics drug challenge tests: predictive value of skin tests.

Journal of investigational allergology & clinical immunology, 2020
BACKGROUND AND OBJECTIVE The study of perioperative drug reactions remains a major challenge both for diagnosis and therapeutic management. Lack of standardization of the study of allergy to general anesthetics and nonexistence of data establishing the ...
P. T. Molina, P. Rojas-Pérez-Ezquerra, B. Noguerado-Mellado, M. B. O. D. Ocaríz, A. Sánchez, M. Mateos, J. M. Z. Ortuno   +6 more
semanticscholar   +1 more source

Awareness about inhalation general anaesthetics among dental students [PDF]

, 2022
Introduction: General anesthesia is a state of medically induced coma or unconsciousness. General anaesthetics are drugs that render a patient unresponsive and unconscious, so that the patient is unaware of surgery and does not move or feel pain while ...
Bharathi, Alagu Rathi, Ganapathy, Dhanraj M., Rakshagan, V.   +2 more
core   +1 more source

New patents on topical anesthetics. [PDF]

, 2014
Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano, CANTISANI, CARMEN, D'ANDREA, Vito, Frascani, F, MACALUSO, LAURA, paolino, giovanni, RICHETTA, Antonio Giovanni   +6 more
core   +1 more source

A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain

Brain Sciences, 2014
The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj   +1 more source

General anesthetic binding mode via hydration with weak affinity and molecular discrimination: General anesthetic dissolution in interfacial water of the common binding site of GABAA receptor

Biophysics and Physicobiology, 2023
The GABAA receptor (GABAAR) is a target channel for the loss of awareness of general anesthesia. General anesthetic (GA) spans a wide range of chemical structures, such as monatomic molecules, barbital acids, phenols, ethers, and alkanes.
Tomoyoshi Seto
doaj   +1 more source

Are volatile anesthetics neuroprotective or neurotoxic? [PDF]

, 2012
Volatile anesthetics are one class of the most commonly used drugs. However, the mechanisms for these drugs to induce anesthesia are not fully understood and have been under intensive investigation.
Zuo, Zhiyi
core   +3 more sources

Early postoperative recovery in operating room after desflurane anesthesia combined with Bispectral index (BIS) monitoring and warming in lengthy abdominal surgery: a randomized controlled study

BMC Anesthesiology, 2018
Background This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy ...
Hong Yu, Lu Zhang, Ye Ma, Hai Yu
doaj   +1 more source