Results 51 to 60 of about 78,545 (352)

Neurotoxicity of General Anesthetics [PDF]

Anesthesiology, 2009
General anesthetics are highly lipid soluble and can dissolve in every membrane, penetrate into organelles and interact with numerous cellular constituents. Their actions have long been considered rapid and fully reversible, with the pharmacodynamic time course of anesthesia dictated solely by the pharmacokinetic profiles of anesthetic uptake and ...
Misha Perouansky, Hugh C. Hemmings, Bruno Riou   +2 more
openaire   +2 more sources

Biochemical parameters of silver catfish (Rhamdia quelen) after transport with eugenol or essential oil of Lippia alba added to the water [PDF]

, 2017
The transport of live fish is a routine practice in aquaculture and constitutes a considerable source of stress to the animals. The addition of anesthetic to the water used for fish transport can prevent or mitigate the deleterious effects of transport ...
A. G. Becker, ALMROTH B.C., AZAMBUJA C.R., B. Baldisserotto, B. M. Heinzmann, BALDISSEROTTO B., BECKER A.G., BECKER A.G., BENOVIT S.C., BLENAU W., BRADFORD M.M., BUEGE J.A., C. C. Menezes, C. C. Zeppenfeld, C. Toni, COOKE S.J., CUNHA M.A., CUNHA M.A., DUBOIS M., ELLMAN G.L., ELLMAN G.L., GONÇALVES A.F.N., GOYAL A.K., HABIG W.H., HARROWER J.R., HUDETZ A.G., INOUE L.A.K.A., INOUE L.A.K.A., J. Salbego, LEUNG L.S., LINTERN M.C., LOWRY O.H., LÓPEZ M.D., MATÉS J.M., MAZZANTI L., MOMMSEN T.P., PANKHURST N.W., PARODI T.V., ROSS L.G., ROUBACH R., SALBEGO J., SALBEGO J., TONI C., UNGVARI Z., V. L. Loro, VALE T.G., VALE T.G., VILLARES JUNIOR G.A., YAN L.J., YONAR M.E., ZAHL I.H.   +50 more
core   +2 more sources

Effect of Nonsteroidal Anti‐Inflammatory Drugs on Sacroiliac Joint Inflammation, as Seen on Magnetic Resonance Imaging, in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones, Alexander N. Bennett, Raj Sengupta, Pedro M. Machado, Helena Marzo‐Ortega, Lorna Aucott, Margaret A. Hall‐Craggs, Timothy J. P. Bray, Alan Bainbridge, Ruaridh M. Gollifer, Gary J. Macfarlane   +10 more
wiley   +1 more source

General anesthetic action profile on the human prefrontal cortex cells through comprehensive single-cell RNA-seq analysis

iScience, 2023
Summary: The cellular and molecular actions of general anesthetics to induce anesthesia state and also cellular signaling changes for subsequent potential “long term” effects remain largely elusive.
Enqiang Chang, Yangyang Wang, Ruilou Zhu, Lingzhi Wu, Yitian Yang, Shuang Zeng, Ningtao Li, Xiaoguo Ruan, Mingyang Sun, Wei Zhang, Jun Zhou, Mengrong Miao, Hui Zhi, Hailin Zhao, Qian Chen, Qizhe Sun, Emer Chang, Albert Chang, Tingting Zhang, Xinfang He, Kan Liu, Songhua Ma, Weizhong Zhu, Youming Zhang, Luca Magnani, Daqing Ma, Jiaqiang Zhang   +26 more
doaj   +1 more source

General Anesthetic Actions on GABAA Receptors [PDF]

Current Neuropharmacology, 2010
General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABA(A) receptor.
Paul S. García, Scott E Kolesky, Andrew Jenkins   +2 more
openaire   +2 more sources

Direct Current Auditory Evoked Potentials During Wakefulness, Anesthesia, and Emergence from Anesthesia [PDF]

, 2001
Direct current auditory evoked potentials (DC-AEPs) are a sensitive indicator of depth of anesthesia in ani-mals. However, they have never been investigated in humans. To assess the potential usefulness of DC-AEPs as an indicator of anesthesia in humans,
Bauer, Herbert, Fitzgerald, Robert, Lamm, Claus, Oczenski, Wolfgang, Stimpfl, Thomas, Vycudilik, Walter   +5 more
core   +1 more source

Time Trends and Predictors of Gout Remission Over 6 Years

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles

Frontiers in Neurology, 2012
Exposure to general anesthetics and antiepileptics during critical stages of brain development causes significant neurotoxicity to immature neurons.
Vesna eJevtovic-Todorovic, Annalisa eBoscolo, Victoria eSanchez, Nadia eLunardi   +3 more
doaj   +1 more source

Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]

, 2018
While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover, David R. Drover, Don A. Vaughn, Don A. Vaughn, M. Bruce MacIver, Mark S. Cohen, Mark S. Cohen, Nicholas T. Ouellette, Sarah L. Eagleman   +8 more
core   +2 more sources

Proportion of Acceptable Symptom State Nearly Tripled With Improvements in Patient‐Reported Outcomes for All Symptom State Subgroups: A Registry Study of More Than 15,000 Patients With Osteoarthritis in Digital Education and Exercise Therapy

Arthritis Care &Research, EarlyView.
Objective This study investigated trajectories of patient acceptable symptom state (PASS) among participants of digital education and exercise therapy for knee and hip osteoarthritis. Methods A longitudinal observational study among individuals aged at least 40 years who participated in the digital program.
Ali Kiadaliri, L. Stefan Lohmander, Amanda E. Nelson, Leif E. Dahlberg   +3 more
wiley   +1 more source