Results 71 to 80 of about 400,675 (266)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Adaptation of Diverse Maize Germplasm to Spring Season Conditions in Northeast China
AgronomyNortheast China (NEC) is a major spring maize (Zea mays L.) growing belt, and the outputs substantially influence national grain production. However, the maize grain yield per unit area has little changes in recent years, partially due to the lack of ...
Yi Li +14 more
doaj +1 more source
Combining ability studies for yield and yield components trait in hybrid rice (Oryza sativa L.) [PDF]
Electronic Journal of Plant Breeding, 2012 Fifty two hybrids were generated from crossing four CMS lines and thirteen restorer lines in line x tester design. Crosses along with parents were evaluated for yield and yield component traits during rabi, 2011 at RARS, Jagtial, Andhra Pradesh ...
P.V. Padmavathi, P.V. Satyanarayana , Lal Ahamed M.,Y. Ashoka Rani and V. Srinivasa Rao
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
GENERAL COMBINING ABILITY EFFECTS FOR REPRODUCTIVE HEAT TOLERANCE IN SNAP BEAN
The Journal of Agriculture of the University of Puerto Rico, 2004 GENERAL COMBINING ABILITY EFFECTS FOR REPRODUCTIVE HEAT TOLERANCE IN SNAP ...
null Timothy G. Porch +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Combining ability analysis for seed yield and component traits in Indian mustard [Brassica juncea (L.) Czern & Coss.] [PDF]
Electronic Journal of Plant Breeding, 2015 Combining ability of eight quantitative traits was studied in 12 lines, 4 testers and 48 F1’s in Line x Tester mating design to know the inheritance pattern of yield attributes of Indian mustard [Brassica juncea (L.) Czern & Coss].
Gideon J. Synrem*, N. R. Rangare, Anil K. Choudhari, Sujeet Kumar and Ibadaiahun Myrthong
doaj
Plant Varieties Studying and Protection, 2016 Purpose. Assessment and selection of self-pollinated S5 maize (Zea mays L.) families with high combining ability and wide adaptive capacity obtained on the basis of specially produced hybrids by crossing elite lines of various genetic plasms with the ...
О. Л. Гайдаш
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Frequency of heterotic hybrids in relation to general combining ability of parents in sweet corn. [PDF]
PeerJ, 2023 Madhunapantula VP +5 more
europepmc +1 more source