Results 41 to 50 of about 7,046,045 (313)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

A Model General Education Science Course Involving Humanities and Sciences, Education, and Medical School Collaboration [PDF]

open access: yes, 2002
This article described an innovative general education biology course for non-science majors, BIOL 102-Science of Heredity (SOH), stressing active student learning and collaboration [1]. The course has three components. The lecture is taught by J.
Chinnici, J. P.
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Why and how to integrate general education with technical and vocational education [PDF]

open access: yesفصلنامه نوآوری‌های آموزشی, 2014
This paper explains the need for the integration of general education with technical and vocational education and provides a framework for such integration. The main problem is a lack of clear understanding and a theoretical framework about the necessity
Ahad Navidi
doaj  

Genel Eğitim Okulları ile Özel Eğitim Uygulama Okullarındaki Türkçe Öğretim Programlarının Karşılaştırmalı İncelenmesi

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi, 2022
Eğitim sistemine yön verebilmek adına yapılan tartışmalardan yola çıkarak, eğitimin verimliliğinin ve kalitesinin artırılması, bireylerin ve toplumun değişen ihtiyaçlarının karşılanması için öğretim programlarının güncel ve dinamik olması önemlidir.
M. Abdulbaki Karaca
doaj  

DETERMINING LINGUISTIC IDENTITY OF ETHNIC GROUPS AS THE INFLUENCING FACTOR ON EDUCATIONAL ACTIVITY (CASE STUDY OF REPRESENTATIVES LIVING IN THE SOUTH OF THE TYUMEN REGION)

open access: yesОбразование и наука, 2018
Introduction. Nowadays, in the modern world there is a marked tendency towards increasing mobility of the population. The problem of regular complex monitoring of migration processes is caused by the need for assimilation of representatives of the ethnic
I. K. Tsalikova, S. V. Pakhotina
doaj   +1 more source

Trends in Undergraduate General Education in the U.S., the Texas Core Curriculum, and Communication Course Requirements [PDF]

open access: yes, 2018
In October 2011, the Texas Higher Education Coordinating Board revised Texas Core Curriculum (TCC) rules impacting all public higher education institutions in Texas. The new rules were implemented in the fall semester of 2014.
Henschel, Sally   +3 more
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Chichester College of Arts, Science and Technology (FEFC inspection report; 72/95 and 43/99) [PDF]

open access: yes, 1999
Comprises two Further Education Funding Council (FEFC) inspection reports for the periods 1994-95 (72/95), and 1998-99 (43/99). The FEFC has a legal duty to make sure further education in England is properly assessed.

core  

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