Results 51 to 60 of about 7,338,251 (307)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Skills development, habits of mind, and the spiral curriculum: A dialectical approach to undergraduate general education curriculum mapping

open access: yesCogent Education, 2016
This essay seeks to contribute to growing discussion concerning the need for more intentional inclusion of habits of mind in curriculum development, particularly in undergraduate general education, and to fuel an examination of the “dialectical ...
Jeffrey W. Murray
doaj   +1 more source

Framing the concept design literacy for a general public

open access: yesFORMakademisk, 2021
Educating the general public to be design literate can be a catalyst for both environmental protection and degradation, human aid and human-made disasters depending on how the scope of design is framed – and how ‘design literacy’ is defined.
Eva Lutnæs
doaj   +1 more source

Assessment in vocational programmes in the further education sector in England: report from the Inspectorate (National survey report, January 1995) [PDF]

open access: yes, 1995
This national survey report is concerned with the assessment of students attending all types of vocational education and training programmes offered by further education sector colleges in England.

core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Challenges of workforce pre-professional training for high-tech sectors of the economy in the system of additional education [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия Философия. Психология. Педагогика
Introduction. The article reveals pre-professional training in secondary schools, which is a complex and multifaceted process aimed at developing students’ professional knowledge, skills and abilities necessary to make an appropriate choice of ...
Kosyrev, Vasiliy P., Gribanov, Igor N.
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Student Perceptions of Teacher-Student Relationships in General and Special Education [PDF]

open access: yes, 2020
Teacher-student relationships (TSRs) have largely been found to significantly impact student performance and achievement (Roorda, Koomen, Spilt, & Oort, 2011). The purpose of this investigation was to identify differences between the TSRs experienced
Bains, Bhawandeep Kaur
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

General Education, Vocational Education, and Labor-Market Outcomes over the Life-Cycle [PDF]

open access: yes
Policy debates about the balance of vocational and general education programs focus on the school-to-work transition. But with rapid technological change, gains in youth employment from vocational education may be offset by less adaptability and thus ...
Hanushek, Eric A.   +2 more
core   +3 more sources

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