Results 141 to 150 of about 8,081,518 (357)

Cross-sectional multicentre study on the cohort of all the French junior lecturers in general practice [PDF]

, 2018
Marie Barais, Catherine Laporte, Matthieu Schuers, Olivier Saint‐Lary, Paul Frappé, Clarisse Dibao-Dina, David Darmon, Tiphanie Bouchez, Julien Gelly   +8 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Editors’ choice: The four most valued articles published in the European Journal of General Practice in 2019

European Journal of General Practice, 2020
Jelle Stoffers, On behalf of the Editorial Board of the European Journal of General Practice   +1 more
doaj   +1 more source

Time, money, and weight loss: a qualitative study exploring patients’ perspectives on randomization for bariatric surgery vs. an intensive non-surgical weight loss program

Trials
Background Randomized controlled trials (RCTs) are foundational in advancing medical knowledge and patient care, offering high-quality evidence on the comparative effectiveness of healthcare interventions.
Sofie Amalie Tomova-Olsen, Marius Brostrøm Kousgaard, Katrine Tranberg Jensen, Susanne Reventlow, Ann-Kathrin Lindahl Christiansen, Kirstine Nyvold Bojsen-Møller, Carsten Dirksen, Gritt Overbeck   +7 more
doaj   +1 more source

Associations between child emotional eating and general parenting style, feeding practices, and parent psychopathology

, 2014
Abby Braden, Kyung E. Rhee, Carol B. Peterson, Sarah A. Rydell, Nancy Zucker, Kerri N. Boutelle   +5 more
openalex   +2 more sources

INNOVATING FOR GENERAL PRACTICE

Australasian Medical Journal, 2013
This editorial will consider the challenge of innovation for healthcare from three perspectives: the general practitioner (GP), the patient and the policy maker. The knowledge, attitudes and beliefs of each, respectively, are likely to affect the type of innovation adopted in practice. Each stakeholder has priorities and needs that must be reflected in
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Use of psychiatric drug treatment services by heroin users from general practice. [PDF]

, 1986
A B Bucknall, J R Robertson, J G Strachan   +2 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source