Results 51 to 60 of about 14,384,400 (302)

General scientific guidance for stakeholders on health claim applications

open access: yesEFSA Journal, 2016
The European Food Safety Authority (EFSA) asked the Panel on Dietetic Products Nutrition and Allergies (NDA) to update the General guidance for stakeholders on the evaluation of Article 13.1, 13.5 and 14 health claims published in March 2011. Since then,
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

General Principle and the Coherence of International Law,

open access: yes, 2019
General Principles and the Coherence of International Law provides a collection of intellectually stimulating contributions from leading international lawyers to the discourse on the role of general principles in international law.
M. Fitzmaurice   +9 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Generalized Compensation Principle

open access: yes, 2017
We generalize the classic concept of compensating variation and the welfare compensation principle to a general equilibrium environment with distortionary taxes. We derive in closed-form the solution to the problem of designing a tax reform that compensates the welfare gains and losses induced by an arbitrary economic disruption. In partial equilibrium,
Tsyvinski, Aleh, Werquin, Nicolas
openaire   +5 more sources

On the Architecture of Systemology and the Typology of Its Principles

open access: yesSystems, 2018
Systems engineering is increasingly challenged by the rising complexity of projects undertaken, resulting in increases in costs, failure rates, and negative unintended consequences.
David Rousseau
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Equivalence as Emerging Principle of EU External Relations Law

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2026 11(2), 857–874 | Article | (Table of Contents) 1. Introduction. – 2. The Application of the Principle of Equivalence in the Financial Services Sector. – 3.
Monica Spatti
doaj   +1 more source

General principles of carotid Doppler ultrasonography [PDF]

open access: yesUltrasonography, 2014
<p>Carotid Doppler ultrasonography is a popular tool for evaluating atherosclerosis of the carotid artery. Its two-dimensional gray scale can be used for measuring the intima-media thickness, which is very good biomarker for atherosclerosis
Whal Lee
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Equity as a General Principle in EU External Relations Law

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2026 11(2), 749–775 | Article | (Table of Contents) 1. Introduction. – 2. Equity at a crossroads in international and EU law. – 2.1.
Samantha Besson
doaj   +1 more source

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