Results 71 to 80 of about 869,087 (312)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
, 2019 Summing up the analysis put forward in Part III of the volume on General Principles and the Coherence of International Law, the contribution aims to provide three perspectives under international investment law through which to assess whether general ...
A. Tanzi
core +1 more source
Protection of workers’ personal data: General principles
, 2022 This working paper gives an overview of legal standards related to personal data protection. It explores trends, principles and good practices and brings them in relation to the world of work. The aim of this working paper is to give a global and updated
Hendrickx, Frank
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
General principles of employment of cavalry.
, 2008 This document on general principles of employment of cavalry highlights information regarding command and leading, reconnaissance, protection, the advance toward contact, mounted combat, dismounted combat, breaking of an engagement and leaving a position,
General Service Schools
core
Human Capital: Key Principles From Nine Private Sector Organizations [PDF]
, 2000 A letter report issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO identified the private sector's key principles for strategically and effectively managing their human capital to provide ...
United States. General Accounting Office.
core
The Volterra Principle Generalized [PDF]
Philosophy of Science, 2017 Michael Weisberg and Kenneth Reisman argue that the Volterra Principle can be derived from multiple predator-prey models and that, therefore, the Volterra Principle is a prime example for robustness analysis. In the current article, I give new results regarding the Volterra Principle, extending Weisberg’s and Reisman’s work, and I discuss the ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source