Results 91 to 100 of about 6,607,101 (361)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Decoupling gravitational sources in general relativity: from perfect to anisotropic fluids [PDF]

open access: yes, 2017
We show the first simple, systematic and direct approach to decoupling gravitational sources in general relativity. As a direct application, a robust and simple way to generate anisotropic solutions for self-gravitating systems from perfect fluid ...
J. Ovalle
semanticscholar   +1 more source

High-precision Relativistic Timescales for Cislunar Navigation

open access: yesThe Astrophysical Journal
We present a unified post-Newtonian framework for relativistic timing and coordinate transformations across the Barycentric, Geocentric, and Lunicentric Celestial Reference Systems ( LCRS ) and six timescales: Barycentric Coordinate Time ( TCB ...
Slava G. Turyshev
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Relativistic Spin Precession in the Compact Double Neutron Star System PSR J1946+2052

open access: yesThe Astrophysical Journal
We observe systematic profile changes in the visible pulsar of the compact double neutron star system PSR J1946+2052 using observations with the Five-hundred-meter Aperture Spherical radio Telescope (FAST). The interpulse of PSR J1946+2052 changed from a
Lingqi Meng   +18 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

On Conformally Coupled General Relativity

open access: yesEPJ Web of Conferences, 2018
A gravity model based on the conformal symmetry is presented. To specify the structure of the general coordinate transformations the Ogievetsky theorem is applied. The nonlinear symmetry realization approach is used.
Arbuzov Andrej, Latosh Boris
doaj   +1 more source

The Dynamics of General Relativity

open access: yes, 2004
This article--summarizing the authors' then novel formulation of General Relativity--appeared as Chapter 7 of an often cited compendium edited by L. Witten in 1962, which is now long out of print.
Arnowitt, R., Deser, S., Misner, C. W.
core   +1 more source

Spherically symmetric elastic bodies in general relativity [PDF]

open access: green, 2023
Artur Alho   +3 more
openalex   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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