Results 81 to 90 of about 263,053 (273)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tests of Gravity Using Lunar Laser Ranging

open access: yesLiving Reviews in Relativity, 2010
Lunar laser ranging (LLR) has been a workhorse for testing general relativity over the past four decades. The three retroreflector arrays put on the Moon by the Apollo astronauts and the French built arrays on the Soviet Lunokhod rovers continue to be ...
Stephen M. Merkowitz
doaj  

General Relativity by Kawaguchi geometry

open access: yesEPJ Web of Conferences, 2013
We construct a parameterisation invariant Lagrange theory of fields up to second order by using multivector bundles and Kawaguchi geometry. In this setup, the spacetime is an dynamical object which is a submanifold of the greater manifold, and the actual
Tanaka Erico
doaj   +1 more source

The Ontology of General Relativity [PDF]

open access: yes, 2019
General Relativity generated various early philosophical interpretations. His adherents have highlighted the "relativization of inertia" and the concept of simultaneity, Kantians and Neo-Kantians have underlined the approach of certain synthetic ...
Sfetcu, Nicolae
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Structural Stability and General Relativity

open access: yesUniverse
We review recent developments in structural stability as applied to key topics in general relativity. For a nonlinear dynamical system arising from the Einstein equations by a symmetry reduction, bifurcation theory fully characterizes the set of all ...
Spiros Cotsakis
doaj   +1 more source

Zel'dovich approximation and General Relativity

open access: yes, 2012
We show how the Zel'dovich approximation and the second order displacement field of Lagrangian perturbation theory can be obtained from a general relativistic gradient expansion in \Lambda{}CDM cosmology.
Rampf, Cornelius, Rigopoulos, Gerasimos
core   +1 more source

Is General Relativity Really General Relativity?

open access: yes
In this short paper we briefly discuss the issue of the theory of general relativity as a supposed generalization of the theory of special relativity to see if general relativity did really generalize special relativity as a relativity theory. The simple conclusion that we reach in this discussion is that the theory of general relativity is not ...
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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