Results 91 to 100 of about 10,399,375 (306)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Relativity and the metrology of time [PDF]

open access: yes, 1997
PhDThe motivation for this work is two-fold: the application of general relativity to the metrology of time on one hand (part II), and the use of the methods and technology of time metrology for tests of relativity on the other (part I).
Wolf, Peter
core   +4 more sources

General relativity: An erfc metric

open access: yesResults in Physics, 2018
This paper proposes an erfc potential to incorporate in a symmetric metric. One key feature of this model is that it relies on the existence of an intrinsic physical constant σ, a star-specific proper length that scales all its surroundings.
Réjean Plamondon
doaj   +1 more source

Matter or geometry as fundamental in relativity theory: How not to teach special relativity [PDF]

open access: yes, 2013
In this paper, I review a number of interpretational frameworks for relativistic phenomena like length contraction and relativity of simultaneity. Of central focus is the book Physical Relativity by Harvey Brown, where Brown advocates a view in which ...
Hoving, Darryl G.
core  

The relativity of inertia and reality of nothing [PDF]

open access: yes, 2008
The determination of inertia by matter is looked at in general relativity, where inertia can be represented by affine or projective structure. The matter tensor T seems to underdetermine affine structure by ten degrees of freedom, eight of which can be ...
Afriat, Alexander   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Tests of Gravity Using Lunar Laser Ranging

open access: yesLiving Reviews in Relativity, 2010
Lunar laser ranging (LLR) has been a workhorse for testing general relativity over the past four decades. The three retroreflector arrays put on the Moon by the Apollo astronauts and the French built arrays on the Soviet Lunokhod rovers continue to be ...
Stephen M. Merkowitz
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Is General Relativity Really General Relativity?

open access: yes
In this short paper we briefly discuss the issue of the theory of general relativity as a supposed generalization of the theory of special relativity to see if general relativity did really generalize special relativity as a relativity theory. The simple conclusion that we reach in this discussion is that the theory of general relativity is not ...
openaire   +1 more source

Pseudo-complex general relativity

open access: yes, 2016
This volume presents an pseudo-complex extension of General Relativity which addresses these issues and presents proposals for experimental examinations in strong fields near a large mass.
Greiner, Walter   +2 more
core   +1 more source

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