Results 151 to 160 of about 6,536,250 (365)
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Inextendibilty of the Maximal Global Hyperbolic Development in Electrogowdy spacetimes
EPJ Web of Conferences, 2013 The problem of determinism in General Relativity appears even if one assumes that the spacetime is globally hyperbolic, i.e. that it contains a hypersurface that is intersected by any causal curve exactly once.
Nungesser Ernesto
doaj +1 more source
Testing general relativity with gravitational-wave catalogs: The insidious nature of waveform systematics. [PDF]
iScience, 2021 Moore CJ +3 more
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
A UNIFIED THEORY OF GENERAL RELATIVITY OF GRAVITATION AND ELECTROMAGNETISM. II [PDF]
, 1956 Luther Pfahler Eisenhart
openalex +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Genesis of general relativity - Discovery of general relativity
, 2012 The intermediate stage of the development of general relativity is inseparable of Marcel Grossmann's mathematical assistance. Einstein acknowledges Grossmann's help during 1912-1914 to the development of general relativity. In fact, as with special relativity so was it with General relativity, Einstein received assistance only from his old friends ...
openaire +2 more sources
Living Reviews in Relativity, 1998 The problem of finding the quantum theory of the gravitational field, and thus understanding what is quantum spacetime, is still open. One of the most active of the current approaches is loop quantum gravity. Loop quantum gravity is a mathematically well-
Rovelli Carlo
doaj
Gravitational waves from disks around spinning black holes: Simulations in full general relativity. [PDF]
Phys Rev D, 2021 Wessel E +4 more
europepmc +1 more source