Results 91 to 100 of about 2,446,651 (342)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Cellular Heterogeneity and IL-17 Pathway Dynamics Reveal Insights into the Transition from Ulcerative Colitis to Colorectal Cancer Through scRNA-Seq Analysis

open access: yesJournal of Inflammation Research
Yaxian Li,1,* Ruochuan Sun,1,* Xiaodong Wang,2 Mengdi Ma,1 Huizhen Wang,1 Bo Yang,1 Yida Lu,3 Yongxiang Li1 1Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2The ...
Li Y   +7 more
doaj  

Arterial vascularization of the colon; a guide to surgical resection

open access: yesJournal of Mind and Medical Sciences
Background. Colorectal cancer is a commonly diagnosed neoplasia in men and women worldwide. This study aims to rigorously map the arterial distribution of the colon in order to assess the implications of vascular patterns in surgical resection.
Iulian Slavu   +9 more
doaj   +1 more source

Current status of international experiences in general surgery residency programs in the United States [PDF]

open access: diamond, 2016
Filipe A. Sobral   +5 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

miR-424 Targets AKT3 and PSAT1 and Has a Tumor-Suppressive Role in Human Colorectal Cancer [Retraction]

open access: yesCancer Management and Research
Fang Y, Liang X, Xu J, Cai X. Cancer Manag Res. 2018;10:6537–6547. We, the Editors and Publisher of the journal Cancer Management and Research, have retracted the published article.
Fang Y, Liang X, Xu J, Cai X
doaj  

Palliative Surgery in General Surgery Clinics

open access: yesBezmiâlem Science, 2022
Adem AKÇAKAYA
doaj   +1 more source

Use of virtual reality in children undergoing surgery

open access: yesFrontiers in Pediatrics
ObjectiveEarly mobilization and exercise after surgery are very important to reduce the impact on respiratory system function. The aim of this study was to compare the effects of early mobilization with virtual reality and conventional physiotherapy ...
Sabiha Bezgin   +5 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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