Results 61 to 70 of about 2,358,271 (346)

Frequency of Predisposing Factor of Nausea and Vomiting After Chest Surgery Under General Anaesthesia [PDF]

open access: yes, 2019
Background: Postoperative nausea and vomiting are common and distressing postsurgical symptoms. These symptoms are of particular concern in outpatient surgery because they may require additional direct resources, such as supplies and antiemetic ...
Bhatti, S. U. (Sami)   +5 more
core   +2 more sources

Quality improvement in the surgery-related processes: Managerial challenges and solutions from hospitals of Iran

open access: yesJournal of Education and Health Promotion, 2020
BACKGROUND: There is a growing global movement toward quality and safety in healthcare and quality improvement (QI) in general surgery. The first step in any QI initiative is identifying the challenges and barriers to achieve such goals and then to ...
Tina Beyranvand   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Epidemiological aspects of surgical site infections in an income country. The case of regional hospital center, Borgou (Benin) [PDF]

open access: yes, 2017
Background: Surgical site infection is frustrating for the care team and depressing for the patient. Objective: To determine the epidemiological aspects of surgical site infections in regional hospital, Borgou.
Akpata, Robert   +10 more
core  

Level of preoperative anxiety in patients scheduled for elective non-cardiac surgery

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: the anesthetic-surgical activity is considered a factor that causes anxiety in the patient to be operated on, it is a frequent, but little assessed event, and is of paramount importance at the moment to administer anesthetics.Objective: to ...
Karell Piñón-García   +4 more
doaj  

Acute Care Surgery Model for Emergency Cholecystectomy [PDF]

open access: yesJournal of Acute Care Surgery, 2016
Purpose Acute care surgery (ACS) models have evolved worldwide over the last decade. However, South Korea has an established trauma system and does not consider the ACS model. This study compares the management and outcome of emergency cholecystectomy in
Myoung Je Song   +7 more
doaj   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Roscoe Reid Graham (1890 to 1948): a Canadian pioneer in general surgery. [PDF]

open access: yes, 2014
Roscoe Reid Graham, a Canadian surgeon trained at the University of Toronto, was a true pioneer in the field of general surgery. Although he may be best known for his omental patch repair of perforated duodenal ulcers-often referred to as the Graham ...
Cowan, MD, Scott W.   +2 more
core   +1 more source

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