Results 61 to 70 of about 2,435,192 (345)
Who should perform thyroid surgery and who should not?
Turkish Archives of Otorhinolaryngology, 2007 This report was prepared to • clarify the markedly increased disputes between the General Surgery Departments and Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) Departments in respect to thyroid surgery, • to discuss the subject in question in ...
Levent Erişen +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Frontiers in PsychologyBackgroundAdverse psychological states in surgical patients can impact outcomes. This study aimed to evaluate mood disorders and associated factors in general surgery inpatients using the Huaxi Emotional Distress Index (HEI).MethodsThis retrospective ...
Jie Yang +10 more
doaj +1 more source
Spinal Versus General Anesthesia for Spine Surgery During the COVID-19 Pandemic: A Case Series [PDF]
, 2023 Seyed Abdolhadi Daneshi +3 more
openalex +1 more source
A Brief Overview of the Life and Work of Lyon Henry Appleby, M.D. (1895-1970). [PDF]
, 2016 The life and work of Dr. Lyon Henry Appleby, M.D., portrays the essence of a devoted clinician committed to scholarly excellence. Born in Deseronto, Ontario, in 1895 and passing in 1970, Dr.
Cowan, Scott W. +3 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Annals of Surgery Open, 2022 Esha Pai, MBBS, MS (General Surgery), MCh. (Surgical Oncology), MRCS +1 more
doaj +1 more source
Change in bowel habit, abdominal pain, and a palpable abdominal mass in a 58‐year‐old female
Clinical Case Reports, 2017 Key Clinical Message Giant colonic diverticulum is a rare complication of diverticulosis, which may present in the acute or chronic setting. Colonic resection and en bloc resection of the diverticulum are the favored management, however, conservative ...
Julian Peacock, Zane Perkins
doaj +1 more source
, 2016 Matthew P. Jenkins, MD, has joined the Division of Plastic Surgery. Dr. Jenkins completed his general surgery residency at Temple University Hospital in 2013 and remained there for fellowship training in Plastic and Reconstructive Surgery.
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source