Results 71 to 80 of about 10,822,568 (398)
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Inefficiency in Delivery of General Surgery to Black Patients: A National Inpatient Sample Study
The Surgery Journal, 2023 Background Racial disparities in outcomes among patients in the United States are widely recognized, but disparities in treatment are less commonly understood. This study is intended to identify treatment disparities in delivery of surgery and
John N. Bliton
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Multimodal management strategies for chronic pain after spinal surgery: a comprehensive review [PDF]
Anesthesia and Pain Medicine“Chronic pain after spinal surgery” (CPSS) is a nonspecific term for cases in which the end result of surgery generally does not meet the preoperative expectations of the patient and surgeon.
Jung-Pil Yoon +3 more
doaj +1 more source
Distribution of RET proto‐oncogene variants in children with appendicitis
Molecular Genetics & Genomic Medicine, 2022 Background In addition to patient‐related systemic factors directing the immune response, the pathomechanisms of appendicitis (AP) might also include insufficient drainage leading to inflammation caused by decreased peristalsis.
Jurek Schultz +7 more
doaj +1 more source
William Edwards Ladd, M.D. (1880-1967): the description of his bands. [PDF]
, 2013 In the early 20th century, an established surgical specialty catering to pediatric surgery did not exist, and pediatric surgical ailments were operated on by general surgeons.
Cowan, MD, Scott W. +4 more
core +1 more source
Characterizing slopes for torus knots [PDF]
, 2012 A slope $\frac pq$ is called a characterizing slope for a given knot $K_0$ in $S^3$ if whenever the $\frac pq$-surgery on a knot $K$ in $S^3$ is homeomorphic to the $\frac pq$-surgery on $K_0$ via an orientation preserving homeomorphism, then $K=K_0$. In
Ni, Yi, Zhang, Xingru
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Applications of controlled surgery in dimension 4: Examples
, 2006 The validity of Freedman's disk theorem is known to depend only on the fundamental group. It was conjectured that it fails for nonabelian free fundamental groups. If this were true then surgery theory would work in dimension four.
Hegenbarth, Friedrich, Repovš, Dušan
core +1 more source