Results 71 to 80 of about 743,035 (307)
In this paper, we study the concomitants of dual generalized order statistics (and consequently generalized order statistics) when the parameters γ1,…,γn are assumed to be pairwise different from Huang–Kotz Farlie–Gumble–Morgenstern bivariate ...
Salem A. Alyami +3 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
An abstract, quantitative theory which connects elements of information —key ingredients in the cognitive proces—is developed. Seemingly unrelated results are thereby unified.
Flemming Topsøe
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A new refinement of Jensen’s inequality with applications in information theory
In this paper, we present a new refinement of Jensen’s inequality with applications in information theory. The refinement of Jensen’s inequality is obtained based on the general functional in the work of Popescu et al.
Xiao Lei, Lu Guoxiang
doaj +1 more source
Algebra generators and information theory
A general simplicity problem in category theory is proposed. A particular example, the simplest choice of generators of an algebra is specified and illustrated by an example.
Kopf, T., Otahalova, R.
openaire +2 more sources
Basic Structure of the General Information Theory [PDF]
The basic structure of the General Information Theory (GIT) is presented in the paper. The main divisions of the GIT are outlined.
Mitov, Ilia +2 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Which entropy for general physical theories? [PDF]
We address the problem of quantifying the information content of a source for an arbitrary information theory, where the information content is defined in terms of the asymptotic achievable compression rate.
Paolo Perinotti +2 more
doaj +1 more source

