Results 51 to 60 of about 962,972 (291)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Predicting conversion to psychosis using machine learning: response to Cannon

Frontiers in Psychiatry
BackgroundWe previously reported that machine learning could be used to predict conversion to psychosis in individuals at clinical high risk (CHR) for psychosis with up to 90% accuracy using the North American Prodrome Longitudinal Study-3 (NAPLS-3 ...
Jason Smucny, Tyrone D. Cannon, Tyrone D. Cannon, Carrie E. Bearden, Carrie E. Bearden, Jean Addington, Kristen S. Cadenhead, Barbara A. Cornblatt, Matcheri Keshavan, Daniel H. Mathalon, Diana O. Perkins, William Stone, Elaine F. Walker, Scott W. Woods, Scott W. Woods, Ian Davidson, Cameron S. Carter   +16 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Marker effects and examination reliability: a comparative exploration from the perspectives of generalizability theory, Rasch modelling and multilevel modelling [PDF]

, 2013
This study looked at how three different analysis methods could help us to understand rater effects on exam reliability. The techniques we looked at were: generalizability theory (G-theory) item response theory (IRT): in particular the Many-Facets ...
Baird, Jo-Anne, Hayes, Malcolm, Johnson, Rod, Johnson, Sandra, Lamprianou, Iasonas   +4 more
core  

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Methodische Grundlagen und Anwendungen der Generalisierbarkeitstheorie in der betriebswirtschaftlichen Forschung [PDF]

, 2007
Die Generalisierbarkeitstheorie stellt einen messtheoretischen Ansatz dar, der im Gegensatz zur klassischen Testtheorie verschiedene Fehlerquellen gleichzeitig berücksichtigen kann.
Eisend, Martin
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Distinguishing between translational science and translational research in CTSA pilot studies: A collaborative project across 12 CTSA hubs

Journal of Clinical and Translational Science
Introduction: The institutions (i.e., hubs) making up the National Institutes of Health (NIH)-funded network of Clinical and Translational Science Awards (CTSAs) share a mission to turn observations into interventions to improve public health.
Margaret Schneider, Amanda Woodworth, Marissa Ericson, Lindsie Boerger, Scott Denne, Pam Dillon, Paul Duguid, Eman Ghanem, Joe Hunt, Jennifer S. Li, Renee McCoy, Nadia Prokofieva, Vonda Rodriguez, Crystal Sparks, Jeffrey Zaleski, Henry Xiang   +15 more
doaj   +1 more source

The Traumatic Brain Injury Model Systems National Database: A Review of Published Research

Neurotrauma Reports, 2021
The Traumatic Brain Injury Model Systems (TBIMS) is the largest longitudinal TBI data set in the world. Our study reviews the works using TBIMS data for analysis in the last 5 years.
Samantha Tso, Ashirbani Saha, Michael D. Cusimano   +2 more
doaj   +1 more source

A Call for Self-Study in Middle Level Teacher Education [PDF]

, 2018
To promote dialogue and in response to calls for rigorous, large-scale, empirical studies as the standard that will move the field of middle level education forward, a collaborative of middle level teacher researchers submit three counterpoints to the ...
Falbe, Kristina N, Kleine, Karynne L. M., Previts, Joanne L.   +2 more
core   +1 more source