Results 61 to 70 of about 367,889 (327)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Background: When ratings of student performance within the clerkship consist of a variable number of ratings per clinical teacher (rater), an important measurement question arises regarding how to combine such ratings to accurately summarize performance.
Clarence D. Kreiter +3 more
doaj +1 more source
Sibling violence: validating a two-factor model of severity in nonoffender populations [PDF]
Objective: Despite a recent surge of academic and clinical interest in sibling violence (SV), valid measures of severity have not been psychometrically established using non-offender populations. This study examined the factor-structure of intentional SV
Khan, Roxanne
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
This study examined the psychometric quality of multiple-choice questions generated by two AI tools, ChatGPT and DeepSeek, within the context of an undergraduate Educational Measurement and Evaluation course. Guided by ten learning outcomes (LOs) aligned
Ceylan Gündeğer Kılcı
doaj +1 more source
Sources of Measurement Error in an ECG Examination: Implications for Performance-Based Assessments [PDF]
Objective: To assess the sources of measurement error in an electrocardiogram (ECG) interpretation examination given in a third-year internal medicine clerkship. Design: Three successive generalizability studies were conducted.
Ferenchick MD, Gary +1 more
core
Replications and Extensions in Marketing – Rarely Published But Quite Contrary [PDF]
Replication is rare in marketing. Of 1,120 papers sampled from three major marketing journals, none were replications. Only 1.8% of the papers were extensions, and they consumed 1.1% of the journal space. On average, these extensions appeared seven years
Armstrong, J. Scott, Hubbard, Raymond
core +3 more sources
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
External univalence for second-order generalized algebraic theories [PDF]
Rafaël Bocquet
openalex +1 more source

