Results 51 to 60 of about 367,889 (327)

Generalizability Theory's Role in Validity Research: Innovative Applications in Health Science Education

open access: yesHealth Professions Education, 2020
Purpose: While generalizability (G) theory is widely recognized as a method for estimating the reliability (precision) of measures, its unique approach to partitioning and quantifying variance also yields validity (accuracy) evidence.
Clarence Kreiter, Nikki Bibler Zaidi
doaj   +1 more source

Un cuestionario para la evaluación psicológica de la ejecución deportiva : estudio complementario entre TCT y TRI [PDF]

open access: yes, 2006
This work shows the construction and scaling of a questionnaire designed to profile the psychological skills of athletes in different sports. The questionnaires theoretical interest lies in the complementary interaction of three current psychometric ...
Hernández Mendo, Antonio
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Estimating the reliability of composite scores [PDF]

open access: yes, 2009
In situations where multiple tests are administered (such as the GCSE subjects), scores from individual tests are frequently combined to produce a composite score.
He, Qingping
core  

Lost in Translation: Piloting a Novel Framework to Assess the Challenges in Translating Scientific Uncertainty From Empirical Findings to WHO Policy Statements. [PDF]

open access: yes, 2017
BACKGROUND:Calls for evidence-informed public health policy, with implicit promises of greater program effectiveness, have intensified recently. The methods to produce such policies are not self-evident, requiring a conciliation of values and norms ...
Benmarhnia, Tarik   +2 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Measuring interaction: An empirical comparison of three OLS regression models [PDF]

open access: yes, 2008
The capacity to correctly assess the existence of interaction is a high-value modeling capability among researchers of information systems (IS), especially those focusing on behavioural paradigm studies.
Saleh Zolait, AZ   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Harm, authority and generalizability: further experiments on the moral/conventional distinction [PDF]

open access: yes, 2010
Certain researchers in the field of moral psychology, following Turiel (1983), argue that children and adults in different cultures make a distinction between moral and conventional transgressions.
Fessler, Daniel MT, Quintelier, Katinka
core   +1 more source

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