Results 41 to 50 of about 103,515 (236)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigating stable and dynamic aspects of student motivation using generalizability theory

open access: yesAustralian Journal of Psychology, 2020
Background The Academic Motivation Scale (AMS) is a commonly used 28‐item measure of motivation orientation. However, the scale has not been examined using methods to distinguish between state and trait aspects of motivation.
Mataroria P. Lyndon   +3 more
doaj   +1 more source

Investigation of ChatGPT and Real Raters in Scoring Open-Ended Items in Terms of Inter-Rater Reliability

open access: yesInternational Journal of Turkish Education Sciences, 2023
The aim of this study is to examine the inter-rater reliability of the responses to open-ended items scored by ChatGPT, an artificial intelligence-based tool, and two real raters according to the scoring keys.
Seda Demir
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ChatGPT vs. DeepSeek: A comparative psychometric evaluation of AI tools in generating multiple-choice questions

open access: yesInternational Journal of Assessment Tools in Education
This study examined the psychometric quality of multiple-choice questions generated by two AI tools, ChatGPT and DeepSeek, within the context of an undergraduate Educational Measurement and Evaluation course. Guided by ten learning outcomes (LOs) aligned
Ceylan Gündeğer Kılcı
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Examining rater and occasion influences in observational assessments obtained from within the clinical environment

open access: yesMedical Education Online, 2016
Background: When ratings of student performance within the clerkship consist of a variable number of ratings per clinical teacher (rater), an important measurement question arises regarding how to combine such ratings to accurately summarize performance.
Clarence D. Kreiter   +3 more
doaj   +1 more source

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