Results 31 to 40 of about 886 (197)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Generalizability and the Theory of Offsetting the Affective Filter
Grounded Theory Review: An International Journal, 2013 When online, post-secondary foreign language learners wrestle with the course material and environment because of their inexperience or misguided expectations, frustration and anxiety often ensue.
Barry Chametzky
doaj +2 more sources
Generalizability Theory Applied to Olympic Taekwondo Combats
European Journal of Human Movement, 2018 Introduction: Generalizability theory (GT) postulates that there are infinite sources of error variation in any measurement. Generalizability analysis is used to reduce and control this measurement error.
Cristina Menescardi +3 more
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Health Professions Education, 2020 Purpose: While generalizability (G) theory is widely recognized as a method for estimating the reliability (precision) of measures, its unique approach to partitioning and quantifying variance also yields validity (accuracy) evidence.
Clarence Kreiter, Nikki Bibler Zaidi
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
PLoS ONE, 2021 BackgroundThe ratings of physician-patient communication are an important indicator of the quality of health care delivery and provide guidance for many important decisions in the health care setting and in health research.
Nicole Röttele +6 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
International Journal of Assessment Tools in EducationThis study examined the psychometric quality of multiple-choice questions generated by two AI tools, ChatGPT and DeepSeek, within the context of an undergraduate Educational Measurement and Evaluation course. Guided by ten learning outcomes (LOs) aligned
Ceylan Gündeğer Kılcı
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