Results 61 to 70 of about 173,392,339 (131)

Role of Inflammation in Arterial Calcification [PDF]

, 2021
Arterial calcification, characterized by calcium phosphate deposition in the arteries, can be divided into intimal calcification and medial calcification.
박성하, Hae-Young Lee, Soyeon Lim, Sungha Park   +3 more
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Characterization of postnatal brain injury and behavioural deficits in a rat model of placental insufficiency‐induced fetal growth restriction

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal growth restriction (FGR) is a common pregnancy complication associated with long‐term neurodevelopmental impairments. Using the reduced uterine perfusion pressure (RUPP) rat model of placental insufficiency‐induced FGR, this study demonstrates that FGR leads to persistent anatomical, histological and behavioural ...
Judit Alhama‐Riba, Caroline G. M. de Theije, Valentina Salvi, Dominique Viveen, Sebastiaan W. T. Corstjens, Marijke. E. J. Achterberg, Yohan van de Looij, Freek E. Hoebeek, Cora H. A. Nijboer   +8 more
wiley   +1 more source

From Genomics to Precision Cardiology: A Comprehensive Review of Clinical Applications and Challenges in Cardiovascular Diseases

Clinical Cardiology, Volume 49, Issue 10, October 2026.
Genomic medicine in cardiovascular care is progressing from established diagnostic applications toward integrated risk prediction, multiomics, and emerging therapeutic strategies. ABSTRACT Background Genomic cardiology is an emerging field integrating genetic, molecular, imaging, and digital health data to improve cardiovascular disease (CVD ...
Neda Mohsen‐Pour, Shiva Esmaeili, Aydin Feyzi, Ali Sharafi, Majid Maleki, Samira Kalayinia   +5 more
wiley   +1 more source

Oral administration of pyrophosphate inhibits connective tissue calcification

EMBO Molecular Medicine, 2017
Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in ABCC6 and ENPP1, respectively, present with extensive tissue calcification due to reduced ...
Dóra Dedinszki, Flóra Szeri, Eszter Kozák, Viola Pomozi, Natália Tőkési, Tamás Róbert Mezei, Kinga Merczel, Emmanuel Letavernier, Ellie Tang, Olivier Le Saux, Tamás Arányi, Koen van de Wetering, András Váradi   +12 more
doaj   +1 more source

A 2 year retrospective study of vegan patients and their pregnancy outcomes in a tertiary level Irish hospital

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 438-444, October 2026.
Abstract Objective Recent previous studies have revealed outcomes of higher risk of low birth weight, small for gestational age, and pre‐eclampsia for vegan pregnant women compared to other diets. This review examined if patients with vegan diet in our tertiary hospital had similar outcomes.
Mona Abdelrahman, Siofra Maher, Stephen W. Lindow, Michael P. O'Connell   +3 more
wiley   +1 more source

Genetics in Arterial Calcification

, 2011
Artery calcification reflects an admixture of factors such as ectopic osteochondral differentiation with primary host pathological conditions. We review how genetic factors, as identified by human genome-wide association studies, and incomplete ...
Frank Rutsch, Yvonne Nitschke, Robert Terkeltaub   +2 more
core   +1 more source

Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets.

, 2010
The analysis of rare genetic disorders affecting phosphate homeostasis led to the identification of several proteins that are essential for the renal regulation of phosphate homeostasis; for example, fibroblast growth factor 23 (FGF23), which inhibits ...
Lorenz-Depiereux, B;Schnabel, D;Tiosano, D;Häusler, G;Strom, TM
core   +2 more sources

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source