Results 51 to 60 of about 127,829 (293)

The early childhood generalized trust belief scale [PDF]

, 2009
The study was designed to develop and evaluate the Early Childhood Generalized Trust Belief Scale (ECGTBS) as a method of assessing 5-to-8-year-olds’ generalized trust.
Betts, LR, Trueman, M, Rotenberg, KJ
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A Comparative Assessment of Regular and Spatial Cross-Validation in Subfield Machine Learning Prediction of Maize Yield from Sentinel-2 Phenology

Eng
The aim of this study is to determine the reliability of regular and spatial cross-validation methods in predicting subfield-scale maize yields using phenological measures derived by Sentinel-2.
Dorijan Radočaj, Ivan Plaščak, Mladen Jurišić   +2 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Spline Estimator in Multi-Response Nonparametric Regression Model

Jurnal Ilmu Dasar, 2010
In many applications two or more dependent variables are observed at several values of the independent variables, such as at time points. The statistical problems are to estimate functions that model their dependences on the independent variables, and to
Budi Lestari, Nyoman Budiantara, Sony Sunaryo, Muhammad Mashuri   +3 more
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An eigenvalue approach for estimating the generalized cross validation function for correlated matrices

, 2019
This works proposes a fast estimate for the generalized cross-validation function when the design matrix of an experiment has correlated columns. The eigenvalue structure of this matrix is used to derive probability bounds satisfied by an appropriate ...
Jbilou, K., Koukouvinos, C., Turek, O., Mitrouli, M.   +3 more
core   +2 more sources

Selection of optimal knot point and best geographic weighted on geographically weighted spline nonparametric regression model

MethodsX
This study proposes the development of a nonparametric regression model combined with geographically weighted regression. The regression model considers geographical factors and has a data pattern that does not follow a parametric form to overcome the ...
Sifriyani, I Nyoman Budiantara, Krishna Purnawan Candra, Marisa Putri   +3 more
doaj   +1 more source