Results 51 to 60 of about 2,407,813 (254)

Domain-specific and total sedentary behaviors associated with psychological distress in older adults

open access: yesPsychology Research and Behavior Management, 2019
Lovro Štefan,1 Mario Baić,2 Goran Sporiš,1 Damir Pekas,2 Nikola Starčević21Faculty of Kinesiology, Department of General and Applied Kinesiology, University of Zagreb, Zagreb, Croatia; 2Faculty of Kinesiology, Department of Sport ...
Štefan L   +4 more
doaj  

The trend of direct medical costs and associated factors in patients with chronic hepatitis B in Guangzhou, China: an eight-year retrospective cohort study

open access: yesBMC Medical Informatics and Decision Making, 2021
Background Although the expenses of liver cirrhosis are covered by a critical illness fund under the current health insurance program in China, the medical costs associated with hepatitis B virus (HBV) related diseases is not well addressed.
Shuo Yang   +10 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Short-term changes in bodily pain and associated baseline factors in patients with fibromyalgia receiving paraprobiotic supplementation: a retrospective observational study

open access: yesFrontiers in Medicine
BackgroundFibromyalgia is characterized by heterogeneous pain trajectories, and short-term clinical improvement may vary across patients. We explored whether routinely collected baseline clinical variables were associated with short-term bodily pain ...
David Castro Corredor   +5 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Effect of Reconstructive Surgery and Functional Brace Treatments on Kinesthesia in Patients with Acute Anterior Cruciate Ligament Tear

open access: yesJournal of Rehabilitation, 2013
Objective: Anterior cruciate ligament (ACL) tear is one of the most common knee injuries. Kinesthesia after ACL tear is impaired. In this study, using hybrid generalized estimation equations (GEE) can be efficient method in analyzing correlated data, we ...
Shahram Ya'ghoubi   +3 more
doaj  

Longitudinal data methods for evaluating genome-by-epigenome interactions in families

open access: yesBMC Genetics, 2018
Background Longitudinal measurement is commonly employed in health research and provides numerous benefits for understanding disease and trait progression over time. More broadly, it allows for proper treatment of correlated responses within clusters. We
Justin C. Strickland   +3 more
doaj   +1 more source

Review of Generalized Estimating Equations by Hardin and Hilbe [PDF]

open access: yes
The new book by Hardin and Hilbe (2003) is reviewed.
Steven Stillman
core  

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

The R Package geepack for Generalized Estimating Equations [PDF]

open access: yes
This paper describes the core features of the R package geepack, which implements the generalized estimating equations (GEE) approach for fitting marginal generalized linear models to clustered data.
Ulrich Halekoh   +2 more
core  

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