Results 51 to 60 of about 163,645 (292)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Novel Decoder for Unknown Diversity Channels Employing Space-Time Codes
EURASIP Journal on Advances in Signal Processing, 2002 We suggest new decoding techniques for diversity channels employing space time codes (STC) when the channel coefficients are unknown to both transmitter and receiver.
Erez Elona, Feder Meir
doaj +1 more source
On sequential versions of the generalized likelihood ratio test [PDF]
Mathematical Proceedings of the Cambridge Philosophical Society, 1979 AbstractIt is shown that the Wilks large sample likelihood ratio statistic λn, for testing between composite hypotheses Θ0 ⊂ Θ1 on the basis of a sample of size n, behaves as n varies like a diffusion process related to an equilibrium Ornstein-Uhlenbeck process, whenever the null hypothesis is true.
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Degenerate‐Generalized Likelihood Ratio Test for One‐Sided Composite Hypotheses [PDF]
Mathematical Problems in Engineering, 2012 We propose the degenerate‐generalized likelihood ratio test (DGLRT) for one‐sided composite hypotheses in cases of independent and dependent observations. The theoretical results show that the DGLRT has controlled error probabilities and stops sampling with probability 1 under some regularity conditions.
Xiang, Dongdong +3 more
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On some aspects of a bivariate alternative zero-inflated logarithmic series distribution
Statistical Theory and Related Fields, 2023 In this paper, we discuss some important aspects of the bivariate alternative zero-inflated logarithmic series distribution (BAZILSD) of which the marginals are the alternative zero-inflated logarithmic series distributions of Kumar and Riyaz (2015.
C. Satheesh Kumar, A. Riyaz
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A Particle Filtering Approach to Change Detection for Nonlinear Systems
EURASIP Journal on Advances in Signal Processing, 2004 We present a change detection method for nonlinear stochastic systems based on particle filtering. We assume that the parameters of the system before and after change are known.
P. S. Krishnaprasad +1 more
doaj +1 more source