Results 51 to 60 of about 499 (215)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Analysis of statistical resolution limit based on Rao test

open access: yesDianxin kexue, 2017
Since the approach of analyzing statistical resolution limit (SRL) based on generalized likelihood ratio test (GLRT) has the problems of high computational complexity and isn’t easy to get the analytical formula of the detection statistics,a method for ...
Minhong SUN   +3 more
doaj   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Low-Grazing Angle Detection in Compound-Gaussian Clutter with Hybrid MIMO Radar

open access: yesInternational Journal of Antennas and Propagation, 2013
This paper focuses on the target detection in low-grazing angle using a hybrid multiple-input multiple-output (MIMO) radar systems in compound-Gaussian clutter, where the multipath effects are very abundant.
Jincan Ding   +4 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Adaptive Energy Detector and Its Application for Mismatched Signal Detection(in English)

open access: yesLeida xuebao, 2015
We investigate several important properties of an Adaptive Energy Detector (AED), which is originally proposed according to the Generalized Likelihood Ratio Test (GLRT), under the assumption that the signal steering vector is completely unknown.
Liu Wei-jian   +5 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Extension of a Fast GLRT Algorithm to 5D SAR Tomography of Urban Areas

open access: yesRemote Sensing, 2017
This paper analyzes a method for Synthetic Aperture Radar (SAR) Tomographic (TomoSAR) imaging, allowing the detection of multiple scatterers that can exhibit time deformation and thermal dilation by using a CFAR (Constant False Alarm Rate) approach.
Alessandra Budillon   +2 more
doaj   +1 more source

Deciphering hierarchical organization of topologically associated domains through change-point testing

open access: yesBMC Bioinformatics, 2021
Background The nucleus of eukaryotic cells spatially packages chromosomes into a hierarchical and distinct segregation that plays critical roles in maintaining transcription regulation.
Haipeng Xing   +3 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

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