Results 51 to 60 of about 517,569 (314)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Generalized growth and approximation errors of entire harmonic functions in \(R^n\), \(n \geq 3\)

open access: yesJournal of Numerical Analysis and Approximation Theory, 2018
In this paper we study the continuation of harmonic functions in the ball to the entire harmonic functions in space \(\mathbb{R}^n\), \(n\geq 3\). The generalized order introduced by M.N.
Devendra Kumar
doaj   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Generating ordered trees

open access: yesTheoretical Computer Science, 1988
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The generalized order (k,t)-Mersenne sequences in groups [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
The purpose of this paper is to determine the algebraic properties of finite groups via a Mersenne-like sequence. Firstly, we introduce the generalized order (k,t)-Mersenne number sequences and study the periods of these sequences modulo m.
E. Mehraban, Ö. Deveci, E. Hincal
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Space–time proper generalized decompositions for the resolution of transient elastodynamic models [PDF]

open access: yes, 2013
In this paper, we investigate ability of proper generalized decomposition (PGD) to solve transient elastodynamic models in space–time domain. Classical methods use time integration schemes and an incremental resolution process.
BOUCINHA, Lucas   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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