Results 191 to 200 of about 24,565 (251)

Epileptic drop attacks: More than just atonic seizures

Epilepsia Open, EarlyView.
Abstract “Drop attacks” are not officially defined by the International League Against Epilepsy. Seizures are characterized by a sudden loss of control over the trunk and posture, leading to falls and injuries, and resolving within a few seconds. Accurately diagnosing the type of seizure is usually difficult due to limitations in clinical documentation
Tomonori Ono, Kazuaki Sato, Ryoko Honda, Hiroshi Otsubo   +3 more
wiley   +1 more source

Medically intractable generalized tonic-clonic or clonic seizures in infancy

, 1995
openaire   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

ENCEVIS: Evaluating the feasibility of an AI‐based algorithm as an assistant to neurophysiologists in clinical practice

Epilepsia Open, EarlyView.
Abstract Objective This study evaluated the performance of the ENCEVIS artificial intelligence (AI)‐based algorithm as a screening tool to predict the presence of ictal and/or interictal epileptiform discharges (IEDs) in electroencephalography (EEG) recordings.
Aleksandre Tsereteli, Natela Okujava, Nikoloz Malashkhia, Tamar Sakvarelidze   +3 more
wiley   +1 more source

[Re: First generalized tonic-clonic seizure].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2016
Martha Seim, Realfsen, Siri M Hylleraas, Bø, Morten I, Lossius, Karl O, Nakken   +3 more
openaire   +3 more sources

Rest‐activity patterns across development in two mouse models of autism and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash, Filip Fredlund, Jenny Wickham, My Andersson, Christine T. Ekdahl   +4 more
wiley   +1 more source

Sustained seizure reduction, treatment simplification, and high retention with cenobamate: A 12‐month real‐world study in refractory and ultra‐refractory focal epilepsy

Epilepsia Open, EarlyView.
Abstract Objective To assess the 12‐month clinical impact of cenobamate (CNB) in adults with drug‐resistant focal epilepsy in clinical practice, exploring whether outcomes differed according to prior antiseizure medication (ASM) exposure. Methods This single‐center, retrospective, observational, real‐world study included 91 adults stratified by the ...
Francesca Cutropia, Maria Teresa Di Claudio, Marta Robustella, Umberto Costantino, Carmela Pia Ferro, Giuseppe Miscio, Elena Conte, Nicola Amoroso, Orazio Nicolotti, Cosimo Damiano Altomare, Massimo Carella, Antonella Liantonio, Paola Imbrici, Giuseppe d'Orsi   +13 more
wiley   +1 more source

Real‐world use of Cenobamate in pediatric drug‐resistant epilepsy: A European multicenter retrospective study

Epilepsia Open, EarlyView.
Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis, Thomas Bast, Stéphane Auvin, Pavel Krsek, Matyas Ebel, Eva Breuer, Mira Beckhaus, Matúš Bašovský, Pavlína Danhofer, Ondřej Horák, Alessandro Orsini, Gonzalo Alonso Ramos Rivera, Hana Medřická, Steffen Syrbe, Angela M. Kaindl   +14 more
wiley   +1 more source

Expanding the electroclinical spectrum of TANC2‐related disorders: Lennox–Gastaut syndrome and related developmental epileptic phenotypes

Epilepsia Open, EarlyView.
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Lorenzo Perilli, Carlotta Stipa, Gianmichele Villano, Laura Licchetta, Leo Strothmann, Robin Tobias Jauss, Gerhard Josef Kluger, Raffaella Minardi, NETRE consortium, Giuseppe Gobbi, Salvatore Grosso, Francesca Bisulli, Pasquale Striano   +12 more
wiley   +1 more source