Results 221 to 230 of about 826,950 (244)

Neonatal‐onset developmental and epileptic encephalopathy: High genetic yield and long‐term outcomes in a multicenter southern European cohort

Epilepsia Open, EarlyView.
Abstract Objective To determine the genetic diagnostic yield, characterize the clinical and genetic landscape, and evaluate long‐term epilepsy, neurodevelopmental, and survival outcomes in a strictly defined cohort of neonatal‐onset developmental and epileptic encephalopathy (DEE).
Júlia Sala‐Coromina, Anna Marcé‐Grau, Gianluca D'Onofrio, Antonella Riva, Roser Pons, Elisabeta Kollia E, Miquel Raspall‐Chaure, Eduardo López‐Laso, Javier López‐Pisón, Edgard Verdura, Agatha Schlüter, Dolors Casellas‐Vidal, Maria Camós‐Carreras, Michele Iacomino, Alberto Spalice, Pasquale Parisi, Alejandro Martínez de la Ossa‐Vela, Mónica Vicente‐Rasoamalala, Aurora Pujol, Vincenzo Salpietro, Pasquale Striano, Alfons Macaya   +21 more
wiley   +1 more source

Surgery After Thermal Ablation of Thyroid Nodules: A Systematic Review of Surgical Risk, Strategy and Pathological Findings

Head &Neck, EarlyView.
ABSTRACT Background Thermal ablation is increasingly used for selected thyroid nodules, but some patients subsequently require thyroidectomy. The effect of prior ablation on surgical risk, operative strategy, and histopathology remains unclear. Methods PubMed/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to May 2026 for studies
Francesco Brucchi, Federica Poli, Beatrice Sperotto, Carla Colombo, Laura Fugazzola, Gianlorenzo Dionigi   +5 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Acute Post‐Partum Psychosis and Dystonia Reveals Late‐Onset MPAN

Movement Disorders Clinical Practice, EarlyView.
Mathilde Lachaume, Audrey Schalk, Nadège Calmels, Christine Tranchant, Ozanne de Andrade, Fabrice Berna, Mathieu Anheim, Thomas Wirth   +7 more
wiley   +1 more source

Perampanel for the treatment of primary generalized tonic-clonic seizures in idiopathic generalized epilepsy

Expert Opinion on Pharmacotherapy, 2016
The non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) - receptor antagonist perampanel (PER) was approved in 2015 for treatment of primary generalized tonic-clonic seizures (pGTCS).
Giorgi Kuchukhidze, Markus Leitinger, Eugen Trinka   +2 more
exaly   +2 more sources

Carbamazepine treatment of generalized tonic–clonic seizures in idiopathic generalized epilepsy [PDF]

Seizure: the Journal of the British Epilepsy Association, 2014
PurposeEvaluate the efficacy of carbamazepine in the treatment of idiopathic generalized epilepsy (IGE).MethodThe response of five patients with IGE, who experienced primarily generalized tonic–clonic seizures which were refractory to multiple ...
Maromi Nei, Scott Mintzer
exaly   +2 more sources

Patterns of muscle activation during generalized tonic and tonic–clonic epileptic seizures

Epilepsia, 2011
Purpose: Tonic seizures and the tonic phase of tonic–clonic epileptic seizures are defined as “sustained tonic” muscle contraction lasting a few seconds to minutes.
Helge Bjarup Dissing Sørensen, Sándor Beniczky, Thomas Sams   +2 more
exaly   +2 more sources

Anticonvulsant drugs for generalized tonic-clonic epilepsy

Expert Opinion on Pharmacotherapy, 2017
Introduction: Primary generalized tonic clonic seizures (pGTCS) are still linked to major concerns for the clinic and hazards for patients suffering from idiopathic generalized epilepsy (IGE), so a quick search of the most effective and appropriate ...
Alberto Verrotti, Francesca Felicia Operto, Giangennaro Coppola   +2 more
exaly   +2 more sources

Automated Algorithm for Generalized Tonic–Clonic Epileptic Seizure Onset Detection Based on sEMG Zero-Crossing Rate [PDF]

IEEE Transactions on Biomedical Engineering, 2012
Patients are not able to call for help during a generalized tonic–clonic epileptic seizure. Our objective was to develop a robust generic algorithm for automatic detection of tonic–clonic seizures, based on surface electromyography (sEMG) signals ...
Helge Bjarup Dissing Sørensen, Sándor Beniczky, Peter Wolf   +2 more
exaly   +2 more sources

Focal electroclinical features in generalized tonic–clonic seizures: Decision flowchart for a diagnostic challenge

Epilepsia
Bilateral tonic-clonic seizures with focal semiology or focal interictal electroencephalography (EEG) can occur in both focal and generalized epilepsy types, leading to diagnostic errors and inappropriate therapy.
Philippe Ryvlin, Sándor Beniczky
exaly   +2 more sources