Results 61 to 70 of about 615,135 (283)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Sensitivity-based chance-constrained Generation Expansion Planning [PDF]

open access: yesElectric Power Systems Research, 2015
Abstract A Generation Expansion Planning problem with load uncertainty is formulated based on joint chance-constrained programming (CCP) and is solved by incorporating sensitivity into iterative algorithms. These algorithms exploit the characteristics of the system and its response to load variations. Sensitivities help to classify buses according to
Manickavasagam, Monishaa   +2 more
openaire   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

An auction framework to integrate dynamic transmission expansion planning and pay-as-bid wind connection auctions. ESRI WP523. January 2016 [PDF]

open access: yes, 2016
Efficient renewables deployment requires the minimisation of both internal generation costs and external transmission expansion planning (TEP) costs.
Devine, Mel T.   +2 more
core   +1 more source

Identification of Generation Expansion Plans in Competitive Markets

open access: yesIEEE Latin America Transactions, 2011
Generation expansion planning plays a key role in the development of a power system. This paper contributes by developing a heuristic based on the results of a simulation model of the Central Interconnected System (SIC), which iteratively optimizes the number of expansion units necessary to accomplish certain assumptions and restrictions that a ...
Cerda, P., Larrain, M., Rudnick, H.
openaire   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Co-Optimization of Generation and AC Transmission Networks, Considering Reactive Power Allocation and Network Power Losses

open access: yesIEEE Access
Generation and transmission network expansion planning (GTNEP) co-optimization models have been developed to enable simultaneous decisions considering investment and operational components.
Jose E. Chillogalli   +5 more
doaj   +1 more source

Distributed Resources Shift Paradigms on Power System Design, Planning, and Operation: An Application of the GAP Model [PDF]

open access: yes, 2019
Power systems have evolved following a century-old paradigm of planning and operating a grid based on large central generation plants connected to load centers through a transmission grid and distribution lines with radial flows.
Callaway, D   +3 more
core  

A welfare analysis of the electricity transmission regulatory regime in Germany [PDF]

open access: yes, 2015
We analyze the current regulatory regime for electricity transmission in Germany, which combines network planning with both cost-plus and revenue-cap regulations.
Kemfert, Claudia   +2 more
core   +2 more sources

Evaluation of uncertainties on generation expansion planning [PDF]

open access: yes2013 IEEE 7th International Power Engineering and Optimization Conference (PEOCO), 2013
In the deregulated power market the generator firms compete with each other to reach the maximum profit. And in this type of power market the investors encounter several uncertain parameters. Demand uncertainty is one of the main parameters can reduce the risk of investing when the planners consider in their planning.
M.T. Askari   +3 more
openaire   +1 more source

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