Results 121 to 130 of about 1,463,381 (333)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Variable Capacity Utilization, Ambient Temperature Shocks and Generation Asset Valuation [PDF]

open access: yes
This paper discusses generation asset valuation in a framework where capital utilization decisions are endogenous. We use real options approach for valuation of natural gas fuelled turbines.
Alexandre Dmitriev, Chung-Li, Wei Zhu
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

N-K Constrained Composite Generation and Transmission Expansion Planning With Interval Load

open access: yesIEEE Access, 2017
The uncertainties of the predicted load demand and N-K contingencies are very significant aspects to composite generation and transmission expansion planning (CGTEP).
Shaoyun Hong   +2 more
doaj   +1 more source

Preferences on Intervals: a general framework

open access: yes, 2005
I present a general framework for the comparison of alternatives to which (possibly) an interval of values is associated. Some representation theorems for the existence of the intervals are discussed as well the possibility ot explicitly take into account situations of hesitation. Some appropriate logical formalisms are discussed for such a purpose.
Ozturk, Meltem, Tsoukias, A.
openaire   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Steady-State Interval Detection and Nonlinear Modeling for Automatic Generation Control Systems

open access: yesIEEE Access, 2019
Automatic generation control systems are designed to adjust electric power outputs of multiple generators simultaneously in accordance with the current load.
Pengfei Cao, Jiandong Wang, Chao Zhang
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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