Results 161 to 170 of about 1,282,208 (307)

Are gamers better laparoscopic surgeons? Impact of gaming skills on laparoscopic performance in "Generation Y" students. [PDF]

open access: yesPLoS One, 2020
Datta R   +11 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Spanish generation in the NLP system 'LOLITA' [PDF]

open access: yes, 1995
The aim of this research has been to modify the NLG module in the NLP system LOLITA to enable it to produce Spanish utterances. Natural Language Generation (NLG) is the production of text in a surface language by the computer in order to meet ...
Fernández, Miquel A.
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Generation Y as wine tourists: their expectations and experiences at the winery cellar door

open access: yes, 2010
Wine tourism and research surrounding it has developed substantially over the last 15 years. The importance for wineries of visitation to cellar doors is recognised by both the tourism and wine industries (Carlsen and Charters, 2006; Mitchell and Hall ...
Fountain, Joanna, Charters, S
core  

Tackling the Matrix Multiplication Micro-kernel Generation with EXO

open access: yes
[EN] The optimization of the matrix multiplication (or GEMM) has been a need during the last decades. This operation is considered the flagship of current linear algebra libraries such as BLIS, OpenBLAS, or Intel OneAPI because of its widespread use in a
Martínez, Héctor   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy