Results 71 to 80 of about 1,282,208 (307)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mid-IR supercontinuum generation from non-silica microstructured optical fibers [PDF]

, 2007
In this paper, the properties of nonsilica glasses and the related technology for microstructured fiber fabrication are reviewed. Numerical simulation results are shown using the properties of nonsilica microstructured fibers for mid-infrared (mid-IR ...
Horak, P., Leong, J.Y.Y., Richardson, D., Petropoulos, P., Richardson, D.J., Monro, T., Ebendorff-Heidepriem, H., Poletti, F., Price, J., Brambilla, G., Price, J.H.V., Leong, J., Flanagan, J., Monro, T.M., Finazzi, V., Feng, X., Flanagan, J.C.   +16 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Managing multi-generation employees at work: understanding inter-generational employee differences with big-five models and their effects on job stress

DIJB (Diponegoro International Journal of Business), 2019
This study aims to determine differences of employee’s personality between generation X and generation Y. We use the big five personality model consists of extraversion, agreableness, conscientiousness, neoriticsm, and openness to experience.
Diaz Haryokusumo, Bambang Setia Wibowo
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Impact of Coffee Tourist Attractions on Visit Intentions of Generation Y and Z

Indonesian Journal of Tourism and Leisure
This study investigates the influence of coffee tourist attractions (CTA) on the visit intentions of Generation Y and Generation Z. Utilizing a quantitative research framework, surveys were conducted to assess how product quality, service quality, and ...
Bentar Sagara Mukti, Tri Kuntoro Priyambodo, Siti Nurul Rofiqo Irwan   +2 more
doaj   +1 more source

Prestige y 11-M : la vertebración política de la gestión de catástrofes [PDF]

, 2007
Between 2002 and 2004 Spain was jolted by two big crisis scenarios with a very different nature but two common characteristics. On one hand, they required an immediate response of some magnitude and complex management. On the other, they both caused a
García Sánchez, Esther, Natera Peral, Antonio, Vanaclocha Bellver, Francisco José, García Sánchez, Ester   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source