Results 91 to 100 of about 821,219 (302)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Young Voters, Abstainers and Unregistered: Generation Z Turnout in a Compulsory System
While young people’s electoral behaviour in voluntary voting systems has been extensively studied, we know little about this in compulsory systems. To investigate, we examine the drivers of voting, not voting and not registering of Generation Z youths in
Martinez i Coma, Ferran +2 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2023 The bachelor thesis Czech Generation Z podcasters deals with podcasting and Czech Generation Z podcasters. In the theoretical part, the phenomenon of podcasting is defined, followed by a summary of the history and podcasting development abroad with an ...
Hnyková, Michaela
core +1 more source
Generation Z and “Quiet Quitting”: Rethinking onboarding in an era of employee disengagement
Multidisciplinary Business ReviewWhy are Generation Z employees quiet quitting? A potential answer is related to Generation Z disen-gagement. Quiet quitting is troublesome for com-panies with growing numbers of young recruits checking out emotionally from work.
Karina Ochis
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Online game-based learning in mathematics education among generation Z: a systematic review [PDF]
<jats:p xml:lang="en">In contemporary education, game-based learning (GBL) has become a captivating instructional method applied across various academic subjects, including mathematics.
Hidayat, Riyan +6 more
core +1 more source