Results 101 to 110 of about 10,007,622 (296)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Generative design for individual orthopaedic insoles: Optimisation of load distribution and additive manufacturing

Current Directions in Biomedical Engineering
Introduction: Generative Design (GD) is an intelligent process that uses algorithms to automatically create optimised, functional and material-efficient structures based on defined parameters and loads. This makes it a valuable tool for the customisation
Schneider Julia, Bouffier Justus, Valerga Puerta Ana Pilar, Völz Diana   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Algorithmic Intimacy: AI Co-authorship and Student Designer identity in Architectural Education

International Journal of Mardin Studies (IJMS)
This study investigates the psychological dimensions of Human-AI collaboration in architectural education through a retrospective analysis of pedagogical documentation and student work from a second-year architectural design studio.
Jasim Azhar
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Initial Model for Generative Design Research: Bringing together Generative Focus Group (GFG) and Experience Reflection Modelling (ERM) [PDF]

, 2015
Understanding people’s experiences and the context of use of a product at the earliest stages of the design process has in the last decade become an important aspect of both the design profession and design education.
TURHAN, Senem, BAKIRLIOĞLU, Yekta, Bakırlıoğlu, Yekta, OĞUR, Dilruba, DOĞAN, Çağla   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Making the case for introducing generative artificial intelligence (AI) into design curricula

The use of generative artificial intelligence (AI) in higher education design programmes is expanding, yet there is little formalized approach to its integration.
Fleischmann, Katja
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A human-machine integrated optimization method for long walkway space

Journal of Asian Architecture and Building Engineering
With the development of cities, the design of long walkway spaces have exposed a series of issues. These spaces suffer from layout inefficiencies due to the complex interaction of multiple factors, affecting walking experiences.
Yating Wang, Zijun Wang, Hui Wang
doaj   +1 more source