Results 181 to 190 of about 10,007,622 (296)

An Analysis on the Use of Image Design with Generative AI Technologies [PDF]

Using the Midjourney platform as the observation object, this study recruited online users and AI platforms for cooperation in order to further investigate the application of generative AI technology in image design and explore the application process of
Archana Balkrishna, Yadav
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Generative design and validation of therapeutic peptides for glioblastoma based on a potential target ATP5A. [PDF]

Brief Bioinform
Qian H, You P, Zeng L, Zhou J, Huang D, Li K, Tu S, Xu L.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evaluating BindCraft for Generative Design of High-Affinity Peptides. [PDF]

ACS Chem Biol
Filius M, Patsos T, Minnee H, Turco G, Chong HE, Liu J, Gnatzy M, Rooth RSM, Liu ACH, Ta RDT, Rijk IHA, Ziani S, Boxman FJ, Pomplun SJ.   +13 more
europepmc   +1 more source

Exploiting Generative Design for 3D Printing of Bacterial Biofilm Resistant Composite Devices. [PDF]

Adv Sci (Weinh), 2021
He Y, Abdi M, Trindade GF, Begines B, Dubern JF, Prina E, Hook AL, Choong GYH, Ledesma J, Tuck CJ, Rose FRAJ, Hague RJM, Roberts CJ, De Focatiis DSA, Ashcroft IA, Williams P, Irvine DJ, Alexander MR, Wildman RD.   +18 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Generative Design of 3D-Printed Biomimetic Interlocking Blocks Inspired by the Cellular 3D Puzzle Structure of the Walnut Shell. [PDF]

Biomimetics (Basel)
Efstathiadis A, Symeonidou I, Tsongas K, Tzimtzimis EK, Tzetzis D.   +4 more
europepmc   +1 more source

Deep generative design of porous organic cages via a variational autoencoder.

Digit Discov, 2023
Zhou J, Mroz A, Jelfs KE.
europepmc   +1 more source

3D printed plates based on generative design biomechanically outperform manual digital fitting and conventional systems printed in photopolymers in bridging mandibular bone defects of critical size in dogs. [PDF]

Front Vet Sci, 2023
Baumgartner D, Schramel JP, Kau S, Unger E, Oberoi G, Peham C, Eberspächer-Schweda M.   +6 more
europepmc   +1 more source