Results 181 to 190 of about 154,226 (313)
Generative design approach to combine architected Voronoi foams with porous collagen scaffolds to create a tunable composite biomaterial. [PDF]
Acta Biomater, 2023 Dewey MJ +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Controlling gene expression with deep generative design of regulatory DNA. [PDF]
Nat Commun, 2022 Zrimec J +13 more
europepmc +1 more source
An Analysis on the Use of Image Design with Generative AI Technologies [PDF]
Using the Midjourney platform as the observation object, this study recruited online users and AI platforms for cooperation in order to further investigate the application of generative AI technology in image design and explore the application process of
Archana Balkrishna, Yadav
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Generative Design and Integrated 3D Printing Manufacture of Cross Joints. [PDF]
Materials (Basel), 2022 Han L, Du W, Xia Z, Gao B, Yang M.
europepmc +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Generative design of de novo proteins based on secondary structure constraints using an attention-based diffusion model. [PDF]
Chem, 2023 Ni B, Kaplan DL, Buehler MJ.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Single Red Blood Cell Hydrodynamic Traps via the Generative Design. [PDF]
Micromachines (Basel), 2022 Grigorev GV +8 more
europepmc +1 more source