Results 161 to 170 of about 154,226 (313)
Molecular analysis and design using multimodal generative artificial intelligence via multi-agent modeling [PDF]
We report the use of a multimodal generative artificial intelligence framework, the X-LoRA-Gemma large language model (LLM), to analyze, design and test molecular design.
Markus, Buehler, Isabella, Stewart
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
GENERATIVE DESIGN IN CULTURAL FLUX: SPATIOTEMPORAL DYNAMICS AND VALUE METRICS
Russian Studies in Culture and SocietyCulture, as the core dimension for value manifestation in generative design, exerts decisive influence on design morphology through its spatiotemporal attributes and structural characteristics.
Wei Weng
doaj +1 more source
Perfect prosthetic heart valve: generative design with machine learning, modeling, and optimization. [PDF]
Front Bioeng Biotechnol, 2023 Danilov VV +6 more
europepmc +1 more source
Benchmarking Study of Deep Generative Models for Inverse Polymer Design [PDF]
Molecular generative models based on deep learning have increasingly gained attention for their ability in de novo polymer design. However, there remains a knowledge gap in the thorough evaluation of these models.
Ying, Li +3 more
core +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Generative design and its role in developing the design of cans and packaging
الاكاديميIn the current study (generative design and its role in developing the design of cans and packaging), the researcher studied generative design and its role in developing the field of can and packaging design, which saves the effort and time needed to ...
Suha Mahmoud Taha, Ali Ghazi Matar
doaj +1 more source
Design Production: Constructing Freeform Designs with Rapid Prototyping [PDF]
, 2005 Creative fields such as architectural design require the production of many candidate ideas for visual evaluation and redesign. This paper presents a method to design and manufacture a free form model at a specific architectural scale in less than a day.
K. Shea, L. Sass
core
Generative design and additive manufacturing in assistive devices : educational strategies for human-centred solutions [PDF]
This paper explores how Generative Design (GD), Additive Manufacturing (AM), and multi-stakeholder design approaches can inform engineering education for assistive technology innovation.
Patiniott, Nicholas +4 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source