Results 161 to 170 of about 10,007,622 (296)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

A Site-Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design. [PDF]

Adv Sci (Weinh)
Luo G, Zhang Q, Wang C, Yi Z, Wang AJ, Tang J, Li M.   +6 more
europepmc   +1 more source

Generative Design and Integrated 3D Printing Manufacture of Cross Joints. [PDF]

Materials (Basel), 2022
Han L, Du W, Xia Z, Gao B, Yang M.
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

AI for Accelerated Materials Discovery: From Generative Design to Autonomous Realization. [PDF]

Chem Rev
Choi J, Kim S, Park J, Choi J, An S, Jung Y.   +5 more
europepmc   +1 more source

Generative design of de novo proteins based on secondary structure constraints using an attention-based diffusion model. [PDF]

Chem, 2023
Ni B, Kaplan DL, Buehler MJ.
europepmc   +1 more source

Generative AI in the design for additive manufacturing of orthotic devices – a literature review

Generative AI and additive manufacturing (AM) are shifting orthotic design from generic devices to data-driven, patient-specific solutions. This paper presents a systematic review of Generative AI in Design for AM (DfAM) for orthotic devices. It examines
Monim, Abdul, Obilanade, Didunoluwa, Törlind, Peter, Törlind, Peter,, Monim, Abdul,, Obilanade, Didunoluwa,   +5 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Sequential Topology Optimization and Generative Design with Finite Element Validation for Lightweight PA6 Roller Conveyor Components. [PDF]

Materials (Basel)
Alhashmi ZAE, Mitrovic A, Tasic M, Golubovic Z, Mitrovic N.   +4 more
europepmc   +1 more source

Single Red Blood Cell Hydrodynamic Traps via the Generative Design. [PDF]

Micromachines (Basel), 2022
Grigorev GV, Nikitin NO, Hvatov A, Kalyuzhnaya AV, Lebedev AV, Wang X, Qian X, Maksimov GV, Lin L.   +8 more
europepmc   +1 more source