Results 141 to 150 of about 154,226 (313)

Human–AI Collaborative Design in Architectural Studios: Evaluating Paradigm Shifts Across the Six Stages of the Design Process

Buildings
Artificial intelligence (AI) is increasingly transforming architectural education, shifting design studios toward human–AI collaborative workflows. This study investigates the impact of AI integration across the six stages of the architectural design ...
Hend Alana, Mohamed Fikry, Asmaa Hasan
doaj   +1 more source

Architectural authorship in generative design [PDF]

, 2007
The emergence of evolutionary digital design methods, relying on the creative generation of novel forms, has transformed the design process altogether and consequently the role of the architect.
Theodoropoulou, A.
core  

Augmented Memory: Sample-Efficient Generative Molecular Design with Reinforcement Learning [PDF]

Sample efficiency is a fundamental challenge in de novo molecular design. Ideally, molecular generative models should learn to satisfy a desired objective under minimal calls to oracles (computational property predictors).
Guo, Jeff, Schwaller, Philippe
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Analysis of the Energy Optimization Method of Apartment Buildings by Using Generative Design in Terms of Integrated Design

Applied Sciences
Improving building energy efficiency has become essential for reducing global greenhouse gas emissions. (1) Background: We aim to strengthen early-stage collaboration among stakeholders based on integrated design principles, rather than relying solely on
So-Yeon Kim, Jong-Ho Lee
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Methodological Framework for Semiconductor Fab Design Using Dynamo-Based Generative Design

Applied Sciences
The rapid growth of the semiconductor industry has created a bottleneck in which traditional manual methods for designing fabrication plants (fabs) cannot keep pace with their high complexity and short technological lifecycles.
Yeongyu Hwang, WonSeok Choi, Minhyuk Jung, Wonho Cho, Jaewook Lee   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Generative Design in Urban Planning with Regard to Local Zoning Regulations: A BIM Case Study

Urban Science
The development of Building Information Modeling (BIM) and Generative Design (GD) methods supported by artificial intelligence opens up new possibilities in the field of urban planning analyses and the verification of land-use compliance with local ...
Andrzej Szymon Borkowski, Filip Pawlikowski, Anna Ptaszek, Patrycja Raczkowska, Wiktoria Winiarska, Natalia Wyrzykowska   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source