Results 121 to 130 of about 425,706 (317)
To Generalize or Not to Generalize? [PDF]
MAJ. Michael J. McMahon +1 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BCSSE report generator 1.17 Latest updated allows for file names to save in pdf with leading ...
BCSSE report generator 1.17
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SLOPPGEN: A Problem Generator for the Two-Dimensional Rectangular Single Large Object Placement Problem With a Single Defect [PDF]
In this paper, a problem generator for the Two-Dimensional Rectangular Single Large Object Placement Problem is presented. The parameters defining this problem are identified and described.
Vera Neidlein, Gerhard Wäscher
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The goal of this paper is to present an approach to Hod Pair Capturing (HPC). $HPC$ is the most outstanding open problem of descriptive inner model theory. More specifically, we introduce two principles, the Direct Limit Independence and the Bounded Direct Limits, and show that they together imply HPC.
openaire +2 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
development of a Free-Piston Linear Generator for use in an Extended-Range Electric Vehicle
This paper presents the development methodology of the Free-Piston Linear Generator. The FPLG is a free-piston combustion engine with an integrated linear generator. The engine can be used as a range-extending device in an electric vehicle.
Friedrich, Horst E., Ferrari, Cornelius
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

