Results 41 to 50 of about 2,343,217 (327)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

A comparative analysis of the microbiome of cigars produced in the Caribbean and China

open access: yesScientific Reports
Fermentation of cigar tobacco leaves involves intense microbial activity, and hence, microorganisms have a significant impact on the quality and flavour of cigars. However, research on the correlation between microbial communities and the sensory quality
Bo Ding   +10 more
doaj   +1 more source

Generic linear perturbations

open access: yes, 2018
In his celebrated paper "Generic projections", John Mather has shown that almost all linear projections from a submanifold of a vector space into a subspace are transverse with respect to a given modular submanifold.
Ichiki, Shunsuke
core   +1 more source

Generic separating sets for 3D elasticity tensors [PDF]

open access: yes, 2018
We define what is a generic separating set of invariant functions (a.k.a. a weak functional basis) for tensors. We produce then two generic separating sets of polynomial invariants for 3D elasticity tensors, one made of 19 polynomials and one made of 21 ...
Auffray, Nicolas   +4 more
core   +4 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Decompositions of ideals of minors meeting a submatrix [PDF]

open access: yes, 2015
We compute the primary decomposition of certain ideals generated by subsets of minors in a generic matrix or in a generic symmetric matrix, or subsets of Pfaffians in a generic skew-symmetric matrix.
Neuerburg, Kent M., Teitler, Zach
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Structuration sémantique du lexique verbal en français langue étrangère chez des apprenants polonais

open access: yesCorela, 2015
Our study deals with verbal acquisition in the acquisition of French as a foreign language. We observe that, when acquiring the verbal lexicon of a foreign language, learners use a large number of generic verbs such as to cut, to do, to break.
Dominika Jagielska
doaj   +1 more source

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