Results 51 to 60 of about 828,807 (306)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Asymptotic measure-expansiveness for generic diffeomorphisms

open access: yesOpen Mathematics, 2021
In this paper, we will assume MM to be a compact smooth manifold and f:M→Mf:M\to M to be a diffeomorphism. We herein demonstrate that a C1{C}^{1} generic diffeomorphism ff is Axiom A and has no cycles if ff is asymptotic measure expansive.
Lee Manseob
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Evaluation of two supplemental zilpaterol hydrochloride sources on meat quality and carcass traits of crossbred Bos indicus bulls in the tropics

open access: yesRevista Mexicana de Ciencias Pecuarias, 2021
It was studied the effect of two zilpaterol hydrochloride (ZH) brands on carcass and meat quality traits of crossbred Bos indicus young bulls under tropical conditions.
Pedro Antonio Alvarado García   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Key Factors for Improving Predictive Accuracy and Avoiding Overparameterization of the PBPK Absorption Model in Food Effect Studies of Weakly Basic Water-Insoluble Compounds in Immediate Release Formulations

open access: yesPharmaceutics
Background/Objectives: Physiologically based pharmacokinetic (PBPK) absorption models are instrumental for assessing drug absorption prior to clinical food effect studies, though discrepancies in predictive and actual outcomes are observed.
Miao Zhang   +5 more
doaj   +1 more source

Analisa Biaya Pengobatan Demam Tifoid Berdasarkan Clinical Pathway Di Rumah Sakit Harapan Bunda

open access: yesJurnal Profesi Medika, 2019
Clinical pathways are used in quality and cost control with indicators of length of stay. Cases of typhoid fever at Harapan Bunda Hospital include the criteria for the first rank of High Volume in 2018 and Problem Prone in the cost of treatment.
Pieter Hazmen   +2 more
doaj   +1 more source

Efficient generic calibration method for general cameras with single centre of projection [PDF]

open access: yes, 2007
Generic camera calibration is a non-parametric calibration technique that is applicable to any type of vision sensor. However, the standard generic calibration method was developed with the goal of generality and it is therefore sub-optimal for the ...
John Mallon   +5 more
core   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

African newspapers reportage of sanctions: analysis of framing and agenda setting

open access: yesRUDN Journal of Studies in Literature and Journalism
International organizations and numerous countries worldwide have implemented punitive measures, often in the form of sanctions, to express disapproval of certain events within a country or to compel change.
Mustapha A. Adeitan
doaj   +1 more source

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