Results 61 to 70 of about 1,135,224 (358)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Structuration sémantique du lexique verbal en français langue étrangère chez des apprenants polonais

Corela, 2015
Our study deals with verbal acquisition in the acquisition of French as a foreign language. We observe that, when acquiring the verbal lexicon of a foreign language, learners use a large number of generic verbs such as to cut, to do, to break.
Dominika Jagielska
doaj   +1 more source

A Generic Workflow for the Data FAIRification Process

Data Intelligence, 2020
The FAIR guiding principles aim to enhance the Findability, Accessibility, Interoperability and Reusability of digital resources such as data, for both humans and machines.
Annika Jacobsen, Rajaram Kaliyaperumal, Luiz Olavo Bonino da Silva Santos, B. Mons, E. Schultes, M. Roos, Mark Thompson   +6 more
semanticscholar   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Long-term outcomes of innovator versus generic melphalan formulation in autologous hematopoietic cell transplantation for multiple myeloma

Hematology/Oncology and Stem Cell Therapy, 2021
Background: Most data on autologous hematopoietic cell transplantation (auto-HCT) in myeloma are based on the use of innovator formulation of melphalan. Comparative bioequivalence and efficacy studies of generic melphalan are lacking.
Deepesh P. Lad, Pankaj Malhotra, Amol N. Patil, Ram V. Nampoothiri, Kripa Shanker Kasudhan, Alka Khadwal, Gaurav Prakash, Arihant Jain, Samir Malhotra, Neelam Varma, Savita Verma Attri, Subhash Varma   +11 more
doaj   +1 more source

Efficient generic calibration method for general cameras with single centre of projection [PDF]

, 2007
Generic camera calibration is a non-parametric calibration technique that is applicable to any type of vision sensor. However, the standard generic calibration method was developed with the goal of generality and it is therefore sub-optimal for the ...
John Mallon, Aubrey K. Dunne, Paul F. Whelan, Dunne, Aubrey K., Mallon, John, Whelan, Paul F.   +5 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Key Factors for Improving Predictive Accuracy and Avoiding Overparameterization of the PBPK Absorption Model in Food Effect Studies of Weakly Basic Water-Insoluble Compounds in Immediate Release Formulations

Pharmaceutics
Background/Objectives: Physiologically based pharmacokinetic (PBPK) absorption models are instrumental for assessing drug absorption prior to clinical food effect studies, though discrepancies in predictive and actual outcomes are observed.
Miao Zhang, Shudong Zhang, Lin Wang, Zhe Zhang, Qin Hu, Dongyang Liu   +5 more
doaj   +1 more source

The Aging Features of Thyrotoxicosis Mice: Malnutrition, Immunosenescence and Lipotoxicity

Frontiers in Immunology, 2022
The problem of aging is mainly the increase of age-related diseases, and elderly patients have longer hospitalization and worse prognosis. Poorer nutritional status and immunosenescence may be predisposing and severe factors.
Qin Feng, Wenkai Xia, Guoxin Dai, Jingang Lv, Jian Yang, Deshan Liu, Guimin Zhang   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source