Results 71 to 80 of about 828,807 (306)

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

open access: yesFEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi   +6 more
wiley   +1 more source

Generic Directed Acyclic Graphs

open access: yes, 2007
Generic algorithms are algorithms using abstract data types. Multiple generic algorithms can be linked together in a directed acyclic graph (generic DAG) so that more complex generic algorithms can be formed.
Gordon Novak   +3 more
core  

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Gilbert Sorrentino à l’école des arts plastiques ?

open access: yesItinéraires, 2015
Colour and the visual are central to the works of the American writer Gilbert Sorrentino (1929-2006). Like the modernist poets, Sorrentino was inspired by the visual arts, which allow for a more direct interpretation of the world, whereas words, being ...
Juliette Nicolini
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

MODERN PECULIARITIES OF MYOCARDIAL CYTOPROTECTION IN THERAPY OF ISHEMIC HEART DISEASE PATIENTS

open access: yesМедицинский совет, 2016
Results of meta-analysis of more than 20 clinical studies of use of various dosages and schemes of indication of trimetazidine to stable ischemic heart disease patients allowed considering the daily dosage of trimetazidine 70 mg as a standard therapeutic
Z. M. SIZOVA, S .K. VLADIMIROV
doaj   +1 more source

Generic Extensions and Generic Polynomials

open access: yesJournal of Symbolic Computation, 2000
In the paper under review the author proves that the existence of generic polynomials and generic extensions [in the sense of \textit{D. J. Saltman}, Adv. Math. 43, 250-283 (1982; Zbl 0484.12004)] are equivalent over an infinite field. Here one calls a monic polynomial \(P(s_1,\dots,s_m;X) \in K(s_1,\dots,s_m)[X]\), where \(s_1,\dots,s_m\) are ...
openaire   +3 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Mathematical and computer modeling of electro-optic systems using a generic modeling approach [PDF]

open access: yes, 2007
The conventional approach to modelling electro-optic sensor systems is to develop separate models for individual systems or classes of system, depending on the detector technology employed in the sensor and the application.
Smith, M.I.   +2 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

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