Results 51 to 60 of about 351,529 (205)

Stemming the Global Trade in Falsified and Substandard Medicines [PDF]

, 2013
Drug safety and quality is an essential assumption of clinical medicine, but there is growing concern that this assumption is not always correct. Poor manufacturing and deliberate fraud occasionally compromises the drug supply in the United States, and ...
Buckley, Gillian J., Gostin, Lawrence O., Kelley, Patrick W.   +2 more
core   +2 more sources

Quantitative Proteomic Analysis Reveals That Arctigenin Alleviates Concanavalin A-Induced Hepatitis Through Suppressing Immune System and Regulating Autophagy

Frontiers in Immunology, 2018
Concanavalin A-induced autoimmune hepatitis is a well-established experimental model for immune-mediated liver injury. It has been widely used in the therapeutic studies of immune hepatitis. The in-depth analysis of dysregulated proteins from comparative
Qin Feng, Qin Feng, Jingchun Yao, Ge Zhou, Wenkai Xia, Jingang Lyu, Xin Li, Tao Zhao, Guimin Zhang, Guimin Zhang, Ningwei Zhao, Ningwei Zhao, Jie Yang, Jie Yang   +13 more
doaj   +1 more source

Teaching of Critical Analysis of Drug Advertisements to Medical Students [PDF]

, 2011
Background: Medical practitioners utilize drug promotional materials from pharmaceutical companies as a major source of information especially in developing countries.
Adiga, S, Bairy, KL, Chogtu, B, Nayak, V
core   +1 more source

Comparing generic drug markets in Europe and the United States: prices, volumes, and spending [PDF]

, 2017
Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United States. Regulators should make it easier for generic drugs to reach the market.
Abboud, Acosta, Alpern, Andersson, Appleby, Austad, Autorité de la Concurrence, Board, Bodenheimer, Campbell, Carpenter, Colgan, Costa-Font, Daemmrich, Danzon, Danzon, Danzon, Danzon, Danzon, Davit, Decollogny, Drummond, Duerden, Dunne, Dunne, Duru, Dyer, Dyer, Dylst, Dylst, Dylst, Ellison, European Commission, European Commission, Fabiano, Federal Trade Commission, Fischer, Fischer, Fischer, Fox, Fox, Furlow, Gagne, Galizzi, Gassman, Gemmill, Gibson, Glied, Gostin, Gouvalas, Greene, Greene, Greene, Greene, Greene, Greene, Haas, Hartung, Hawkes, Hawkes, Hawkins, Hollis, Howard, Huscher, IMS Health, Jaret, Johansen, Johnston, Kamerow, Kanavos, Kanavos, Kanavos, Kanavos, Kanavos, Kantarjian, Kantarjian, Kesselheim, Kesselheim, Kesselheim, Kesselheim, Kesselheim, Kesselheim, Kesselheim, Lee, Lee, Leopold, Leopold, Light, Luo, Luo, McCarthy, McCarthy, McCarthy, McKee, Merino, Milne, Naci, Neumann, O'Brien, Obama, Obama, Organisation for Economic Co-operation and Development (OECD), Organisation for Economic Co-operation and Development (OECD), Panteli, Puig-Junoy, Rada, Rashidian, Reardon, Rosenberg, Ross, Sarpatwari, Sarpatwari, Shrank, Shrank, Shrank, Shrank, Shrank, Shrank, Simoens, Skaltsas, Socha-Dietrich, Somers, Stabile, Tobbell, Tobbell, Tobbell, Toverud, Treasure, United States Government Accountability Office, US Department of Health & Human Services, Vogler, Vogler, Vogler, Wharam, Wilensky, Wilensky, Wirtz, Wolfe, Wouters, Wouters, Yeh, Zhang   +141 more
core   +1 more source

Biocatalytic kinetic resolution for efficient and enantioselective synthesis of δ-haloalcohols and tetrahydrofurans

Communications Chemistry
Expanding biocatalytic reactions to access previously inaccessible chemical transformations is of significant demand. Halohydrin dehalogenases represent a class of remarkably versatile biocatalysts that have been successfully explored in the asymmetric ...
Yuan-Fei Wang, Xia Hua, Zhang-Yang Wang, Xiao Jin, Hui-Hui Wang, Yong-Zheng Chen, Nan-Wei Wan   +6 more
doaj   +1 more source

Effects of gut microbiota dysbiosis on the metabolism and pharmacokinetics of losartan in rats: from endogenous to ceftriaxone-induced dysbiosis

Frontiers in Microbiology
IntroductionGut microbiota plays a key role in drug metabolism. While gut microbiota dysbiosis is known to contribute to hypertension pathogenesis, its impact on drug metabolism remains poorly considered.
Jiaxuan Xia, Jiaxuan Xia, Jiaxuan Xia, Yibao Jin, Yanjun Hong, Yuefeng Zhang, Meifang Li, Houshuang Huang, Xu Cai, Dan Li, Bing Wang, Zhiyong Xie   +11 more
doaj   +1 more source

It Is Emphatically the Province and Duty of State Courts to Say What Tort Law Is [PDF]

, 2019
Following the U.S. Supreme Court’s 2011 decision in PLIVA, Inc. v. Mensing, consumers of generic prescription drugs suffering from unwarnedof side effects largely remain without an avenue of legal recourse due to their inability to sue their own ...
Choi, Sijin
core   +1 more source

An encounter between metal ions and natural products: natural products-coordinated metal ions for the diagnosis and treatment of tumors

Journal of Nanobiotechnology
Natural products-coordinated metal ions to form the nanomedicines are in the spotlight for cancer therapy. Some natural products could be coordinated with metal ions forming nanomedicines via simple and green environmental self-assembly, which not only ...
Xinyue Liu, Suyi Liu, Xingyue Jin, Haifan Liu, Kunhui Sun, Xiongqin Wang, Meifang Li, Ping Wang, Yanxu Chang, Tiejie Wang, Bing Wang, Xie-an Yu   +11 more
doaj   +1 more source

Schering-Plough Corp. v. Federal Trade Commission: Eleventh Circuit Rejects the FTC’s Position on “Reverse Payments” in Patent Suit Settlements [PDF]

, 2005
In recent years, the Federal Trade Commission (“FTC” or the “Commission”) has investigated several settlement agreements between pioneer and generic drug manufacturers involving “reverse payments.” In the view of the FTC, reverse payments are cash that a
Burling, James, Ehlermann, Claus-Dieter, Kim, Suyong, Kolasky, William, Melamed, Douglas, Quack, Ulrich, Ratliff, John   +6 more
core   +1 more source

Nanocarriers based therapy and diagnosis of brain diseases: cross the blood-brain barrier

Science and Technology of Advanced Materials
The blood-brain barrier (BBB) is the protective interface that isolates the central nervous system from circulating blood, which restricts approximately 98% of small molecule drugs and nearly all large molecules from entering the brain.
Lijun An, Jinwei Zhang, Xiaobo Wang, Yuanyuan Ge, Kunhui Sun, Junlin Dong, Ping Wang, Wei Li, Meifang Li, Xuelei Hu, Bing Wang, Xie-An Yu   +11 more
doaj   +1 more source