Results 141 to 150 of about 80,629 (260)

A Generalized Framework for Data‐Efficient and Extrapolative Materials Discovery for Gas Separation

Advanced Intelligent Discovery, EarlyView.
This study introduces an iterative supervised machine learning framework for metal‐organic framework (MOF) discovery. The approach identifies over 97% of the best performing candidates while using less than 10% of available data. It generalizes across diverse MOF databases and gas separation scenarios.
Varad Daoo, Jayant K. Singh
wiley   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

Advanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri, Leala Carbonneau, Eric M. Roberts, Alison W. Roberts, Candace H. Haigler, Alexey V. Gulyuk, Yaroslava G. Yingling   +6 more
wiley   +1 more source

Exploring SARS-CoV‑2 Spike RBD Pockets as Targets for Generic Drugs: A Combined Computational, Biophysical, and Biological Approach. [PDF]

ACS Omega
García-Marín J, Francés-Gómez C, Forcada-Nadal A, Adhav A, Marco-Marín C, Rubio V, Marina A, Llácer JL, Geller R, Martín-Santamaría S.   +9 more
europepmc   +1 more source

Taguchi–Bayesian Sampling: A Roadmap for Polymer Database Construction Toward Small Representative Machine Learning

Advanced Intelligent Discovery, EarlyView.
This article establishes a Taguchi–Bayesian sampling strategy to reconstruct polymer processing–property landscape at minimal sampling cost, generically building the roadmap for materials database construction from sampling their vast design space. This sampling strategy is featured by an alternating lesson between uniformity and representativeness ...
Han Liu, Liantang Li
wiley   +1 more source

Shortages of Essential Generic Drugs with Limited Competition. [PDF]

J Gen Intern Med
Martin MJ, Rome BN, Kesselheim AS, Lalani HS.   +3 more
europepmc   +1 more source

Evolution of Physical Intelligence Across Scales

Advanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu, Tianyun Huang, Aming Li, Pengyu Lv, Tingting Qin, Wenhui Chen, Hui Wei, Huiling Duan   +7 more
wiley   +1 more source

Physicians' Knowledge and Attitude about Generic Drugs in the Republic of Kazakhstan. [PDF]

Med J Islam Repub Iran
Nakipov Z, Kaliyeva D, Turgambayeva A, Kerimbayeva Z, Arystanov Z, Arystanova T, Ivanchenko N, Awadalla NJ.   +7 more
europepmc   +1 more source

Generic Drugs [PDF]

JAMA, 2016
openaire   +1 more source

Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents

Advanced Intelligent Discovery, EarlyView.
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer, Muhammad Nabeel Asim, Shan Munir, Andreas Dengel   +3 more
wiley   +1 more source

Generic Drugs and the Struggle to Compete: The Role of Skinny Labels. [PDF]

Clin Ther
Boumil MM, Beninger P.
europepmc   +1 more source