Results 31 to 40 of about 1,092,358 (244)
The propagation of perturbations in rewired bacterial gene networks [PDF]
Nature Communications, 2015 AbstractWhat happens to gene expression when you add new links to a gene regulatory network? To answer this question, we profile 85 network rewirings inE. coli.Here we report that concerted patterns of differential expression propagate from reconnected hub genes.
Francesco M. Mancuso +11 more
openaire +8 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Evolution of host support for two ancient bacterial symbionts with differentially degraded genomes in a leafhopper host. [PDF]
, 2018 Plant sap-feeding insects (Hemiptera) rely on bacterial symbionts for nutrition absent in their diets. These bacteria experience extreme genome reduction and require genetic resources from their hosts, particularly for basic cellular processes other than
Bennett, Gordon M +2 more
core
Current Biology, 1999 DNA transfer between related bacterial species is enhanced by species-specific uptake sequences. These sequences have been used to identify genes that have been transferred from Haemophilus to Neisseria, providing a clear example of interspecific transfer of DNA in the evolution of the pathogenic Neisseria.
Saunders, N., Hood, D., Moxon, E.
openaire +4 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Dramatic Increases of Soil Microbial Functional Gene Diversity at the Treeline Ecotone of Changbai Mountain. [PDF]
, 2016 The elevational and latitudinal diversity patterns of microbial taxa have attracted great attention in the past decade. Recently, the distribution of functional attributes has been in the spotlight.
Chu, Haiyan +7 more
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Host specificity of the plant growth-promoting cooperation between Azospirillum and rice [PDF]
, 2013 1. Introduction. Host specificity is a fundamental concept in understanding evolutionary processes leading to intimate interactions between bacteria and plants.
Borland, Stéphanie +5 more
core
Bacterial gene regulation: an overview [PDF]
Microbiology Australia, 2006 Bacteria are highly efficient and metabolically flexible organisms, with their genomes providing them with the ability to adapt to many different environmental conditions. For example, pathogens like Escherichia coli and Clostridium perfringens grow and survive very well in water and soil, respectively, but are also highly adapted to growth in the ...
Julian I. Rood, John K. Davies
openaire +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source