Results 71 to 80 of about 1,208,813 (315)

The VgrG Proteins Are "à la Carte" Delivery Systems for Bacterial Type VI Effectors [PDF]

, 2014
The bacterial type VI secretion system (T6SS) is a supra-molecular complex akin to bacteriophage tails, with VgrG proteins acting as a puncturing device. The Pseudomonas aeruginosa H1-T6SS has been extensively characterized.
Allsopp, LP, Filloux, A, Hachani, A, Oduko, Y   +3 more
core   +2 more sources

Symbiotic outcome modified by the diversification from 7 to over 700 nodule specific cysteine rich peptides [PDF]

, 2020
Legume-rhizobium symbiosis represents one of the most successfully co-evolved mutualisms. Within nodules, the bacterial cells undergo distinct metabolic and morphological changes and differentiate into nitrogen-fixing bacteroids.
Achom, Mingkee, Gifford, Miriam L., Lagunas, Beatriz, Roy, Proyash, Wilkinson, Helen   +4 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The fate of new bacterial genes [PDF]

FEMS Microbiology Reviews, 2009
Bacteria experience a continual influx of novel genetic material from a wide range of sources and yet their genomes remain relatively small. This aspect of bacterial evolution indicates that most newly arriving sequences are rapidly eliminated; however, numerous new genes persist, as evident from the presence of unique genes in almost all bacterial ...
Chih-Horng, Kuo, Howard, Ochman
openaire   +2 more sources

Analysis of differentially expressed genes in bacterial and fungal keratitis

Indian Journal of Ophthalmology, 2020
Purpose: This study was aimed at identifying differentially expressed genes (DEGs) in bacterial and fungal keratitis. The candidate genes can be selected and quantified to distinguish between causative agents of infectious keratitis to improve ...
Rui Tian, He Zou, Lufei Wang, Lu Liu, Meijiao Song, Hui Zhang   +5 more
doaj   +1 more source

Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant? [PDF]

, 2009
The expansion of genome sequencing projects has produced accumulating evidence for lateral transfer of genes between prokaryotic and eukaryotic genomes. However, it remains controversial whether these genes are of functional importance in their recipient
Vera ID Ros, Gregory DD Hurst, PJ Keeling, H Ochman, MJ Pallen, K Fenn, JC Hotopp, N Kondo, N Nikoh, M Blaxter, N Nikoh, ME Rumpho, L Klasson, M Woolfit, DO Daley, NA Moran, D Bensasson, EA Gladyshev   +17 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Evolution of Bacterial Gene Transfer Agents [PDF]

Frontiers in Microbiology, 2018
AbstractBacterial gene transfer agents (GTAs) are small virus-like particles that package DNA fragments and inject them into cells. They are encoded by gene clusters resembling defective prophages, with genes for capsid head and tail components. These gene clusters are usually assumed to be maintained by selection for the benefits of GTA-mediated ...
Redfield, Rosemary J., Soucy, Shannon M.
openaire   +3 more sources

Genome sequence of the pattern forming Paenibacillus vortex bacterium reveals potential for thriving in complex environments [PDF]

, 2010
Background: The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures.
Sirota-Madi, A., Olender, T., Helman, Y., Ingham, C., Brainis, I., Roth, D., Hagi, E., Brodsky, L., Leshkowitz, D., Galatenko, V., Nikolaev, V., Mugasimangalam, R.C., Bransburg-Zabary, S., Gutnick, D.L., Lancet, D., Ben-Jacob, E.   +15 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source