Results 91 to 100 of about 1,208,813 (315)

Antibiotic Resistance Genes and Bacterial Communities of Farmed Rainbow Trout Fillets (Oncorhynchus mykiss)

Frontiers in Microbiology, 2020
The rise of antibiotic resistance is not only a challenge for human and animal health treatments, but is also posing the risk of spreading among bacterial populations in foodstuffs.
Nicolas Helsens, Nicolas Helsens, Ségolène Calvez, Hervé Prevost, Agnès Bouju-Albert, Aurélien Maillet, Albert Rossero, Dominique Hurtaud-Pessel, Monique Zagorec, Catherine Magras   +9 more
doaj   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Molecular Marker Detection and Analysis of Resistance to Bacterial Blight in 72 Rice Germplasms

Guangdong nongye kexue
【Objective】In order to address the challenges posed by bacterial blight to the safety of rice production and to clarify the status of bacterial blight resistance genes in 72 rice germplasm materials.【Method】The total DNA of 72 rice germplasm materials ...
Ying HE, Zeliang XU, Hong ZHANG, Hongkai ZHOU, Junjie MO, Shan YANG   +5 more
doaj   +1 more source

Bacteria under SOS evolve anticancer phenotypes

Infectious Agents and Cancer, 2010
Background The anticancer drugs, such as DNA replication inhibitors, stimulate bacterial adhesion and induce the bacterial SOS response. As a variety of bacterial mutants can be generated during SOS, novel phenotypes are likely to be selected under the ...
Weitao Tao, Dallo Shatha F
doaj   +1 more source

The inheritance of resistance to bacterial leaf spot of lettuce caused by Xanthomonas campestris pv. vitians in three lettuce cultivars. [PDF]

, 2014
Lettuce yields can be reduced by the disease bacterial leaf spot (BLS) caused by the pathogen Xanthomonas campestris pv. vitians (Xcv) and host resistance is the most feasible method to reduce disease losses. The cultivars La Brillante, Pavane and Little
Antonise, Rudie, Bull, Carolee T, Hayes, Ryan J, Michelmore, Richard W, Trent, Mark A, Truco, Maria Jose   +5 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species [PDF]

, 2019
Acidovorax citrulli is the causal agent of bacterial fruit blotch (BFB), a serious threat to cucurbit crop production worldwide. Based on genetic and phenotypic properties, A.
Chen, Gong, Mateus da Silva, Gustavo, Pérez Montaño, Francisco de Asís, Rosenberg, Tally, Santos García, Diego, Yang, Rongzhi, Zhao, Mei   +6 more
core   +1 more source

Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance [PDF]

, 2020
BACKGROUND:The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Bu, Ji-Hye, Cha, Chang-Jun, Cha, Ju-Hee, Hwang, Eun-Mi, Kim, Dae-Wi, Kim, Yong-Seok, Lee, Do-Hoon, Lee, Kihyun, Quince, Christopher, Seong, Hoon Je, Sul, Woo Jun, Thawng, Cung Nawl, Wellington, Elizabeth M. H.   +12 more
core   +1 more source